普通级Z:ZCLA长爪沙鼠在11个生化基因位点多态性的初步研究  

Elementary study on Genetic Diversity of Biochemical Gene Markers of Z:ZCLA Mongolian Gerbil

作　　者：刘月环[1] 柯贤福[1] 楼琦[1] 周莎桑[1] 萨晓婴[1] 

机构地区：[1]浙江省医学科学院浙江省实验动物中心,杭州310013

出　　处：《实验动物与比较医学》2006年第3期165-168,共4页Laboratory Animal and Comparative Medicine

基　　金：浙江省医药卫生基金(2001ZX014)

摘　　要：目的探讨Z:ZCLA长爪沙鼠生化基因位点的多态性。方法用Gpd-1、Es-1、Es-2、Es-3、Es-4、Es-6、Es-8、Es-9、Es-10、Akp-1、Idh-1、Mod-1、Ce-2、Pgm-1、Gpi-1、Car-2、Hbb、Trf、Cs-1等19个生化标记位点的乙酸纤维素膜电泳技术研究了普通级Z:ZCLA长爪沙鼠的遗传多态性。结果Z:ZCLA长爪沙鼠在Es-1、Car-2、Hbb、Gpi-1、Cs-1、Ce-2、Id-l、Mod-1上呈单态性,在Es-2,Es-3,Es-4,Es-6,Es-8,Es-9,Es-10,Gpd-1,Pgm-1,Trf,Akp-1个位点上呈现多态性,等位基因从2￣4个不等,平均等位基因数3.0。结论目前本群遗传多样性水平处于中度多态。Objective To probe into the genetic diversity of the conventional closed colony of Z：ZCLA Mongolian gerbil. Methods The polymorphism of the conventional closed colony of Z：ZCLA Mongolian gerbil（sample content--100 individual） was studied by 19 biochemical gene markers and recorded their characters. Results Among the 19 biochemical loci, The locus Es-1, CarL-2, Hbb, Gpi-1, Cs-1, Ce-2,Id-l,Mod-1 had only one allele, while the locus Es-2, Es-3, Es-4, Es-6, Es-8, Es-9, Es-10, Gpd, Pgm, Trf and Akp-1 had two to four alleles, respectively. Average allele number was recorded as 3.0. Conclusion The conventional closed colony of Z： ZCLA Mongolian gerbil has the medium genetic diversity.

关 键 词：Z:ZCLA长爪沙鼠 生化基因位点 遗传多态性 

分 类 号：Q953[生物学—动物学]