LADA一级亲属GAD-Ab、IA-2Ab与CPH-Ab联合检测的价值  

Valuation of combined testing of GAD-Ab, IA-2Ab and CPH-Ab in first-degree relatives of LADA

作　　者：邓志明[1] 周智广[1] 黄干[1] 亓海英[1] 王建平[1] 谭少珍[1] 严晔华[1] 李莉蓉[1] 

机构地区：[1]中南大学湘雅二医院内分泌科,中南大学糖尿病中心,中南大学代谢内分泌研究所

出　　处：《中国糖尿病杂志》2006年第4期297-298,共2页Chinese Journal of Diabetes

基　　金：国家自然科学基金资助项目(39370343);卫生部优秀青年科技人才专项基金资助项目(Q9420)

摘　　要：采用放射配体法检测128例LADA一级亲属的GAD-Ab、IA-2Ab和CPH-Ab,发现GAD-Ab和IA-2Ab的检出率与欧美高加索人及我国T1DM一级亲属接近,三种抗体联合检测可提高对LADA一级亲属筛查的敏感性。The prevalences of GAD-Ab and IA-2Ab in first-degree relatives of LADA patients were nearly close to those of T1DM first-degree relatives in European and American Caucasians and Chinese. The combined testing of GAD-Ab, IA-2Ab and CPH-Ab was superior to single antibody testing.

关 键 词：成人隐匿性自身免疫性糖尿病 一级亲属 胰岛自身抗体 联合检测 

分 类 号：R587.1[医药卫生—内分泌]