异常子宫出血药物治疗和子宫切除术治疗比较的随机试验:药物或手术(Ms)的资源使用  

Randomized trial of medical treatment versus hysterectomy for abnormal uterine bleeding:Resource use in the Medicine or Surgery (Ms) trial

作　　者：Showstack J. Learman L.A. 张旸 

机构地区：[1]Department of Medicine, University of California, San Francisco, CA, United States Dr

出　　处：《世界核心医学期刊文摘（妇产科学分册）》2006年第9期5-5,共1页Core Journal in Obstetrics/Gynecology

摘　　要：Objective: This study was undertaken to compare resource use outcomes for participants in the Medicine or Surgery (Ms)- randomized trial. Study design: In a randomized controlled trial, we compared resources used during a 24- month follow-up period by women with abnormal uterine bleeding who were randomly assigned to either expanded medical treatment or hysterectomy. Results: Women randomly assigned to hysterectomy used significantly more resources (medicine = ＄ 4479, hysterectomy = ＄ 6777; P = .03), with almost all the difference caused by the hysterectomy procedure. Fifty- three percent of women randomly assigned to medicine had a hysterectomy during the follow- up period; women who were able to continue on medical therapy had mean total resource use of ＄ 2595 compared with ＄ 6128 for medicine patients who eventually had surgery. Conclusion: For women with abnormal uterine bleeding refractory to cyclic medroxyprogesterone acetate, compared with expanded medical treatment, hysterectomy increases resource use significantly and results in better clinical and 6- month quality- of- life outcomes.Objective： This study was undertaken to compare resource use outcomes for participants in the Medicine or Surgery （Ms） - randomized triM. Study design： In a randomized controlled trial, we compared resources used during a 24 - month follow-up period by women with abnormal uterine bleeding who were randomly assigned to either expanded medical treatment or hysterectomy. Results： Women randomly assigned to hysterectomy used significantly more resources （medicine = $4479, hysterectomy = $6777; P = .03）, with almost all the difference caused by the hysterectomy procedure. Fiftythree percent of women randomly assigned to medicine had a hysterectomy during the follow- up period; women who were able to continue on medical therapy had mean total resource use of $2595 $6128 for medicine patients who eventually had surgery. Conclusion： For women with abnormal uterine bleeding refractory to cyclic medroxyprogesterone acetate, compared with expanded medical treatment, hysterectomy increases resource use significantly and results in better clinical and 6 - month quality - of - life outcomes.

关 键 词：子宫切除术后 子宫切除手术 异常子宫出血 药物治疗 随机试验 资源 随机对照试验 醋酸甲羟孕酮 

分 类 号：R713.4[医药卫生—妇产科学]