妊娠期及产后静脉血栓栓塞的发生率、危险因素及死亡率  

Venous thromboembolism during pregnancy and the postpartum period:Incidence, risk factors, and mortality

作　　者：James A.H. Jamison M.G. Brancazio L.R. Myers E.R. 李奎 

机构地区：[1]Divisions of Maternal-Fetal Medicine, Dr

出　　处：《世界核心医学期刊文摘（妇产科学分册）》2006年第9期27-27,共1页Core Journal in Obstetrics/Gynecology

摘　　要：Objective: The purpose of this study was to estimate the incidence,risk factors, and mortality from pregnancy-related venous thromboembolism. Study design: The Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project of the Agency for Healthcare Research and Quality for the years 2000 to 2001 was queried for all pregnancy-related discharges with a diagnosis of venous thromboembolism. Results: The rate of venous thromboembolism was 1.72 per 1000 deliveries with 1.1 deaths per 100,000. The risk of venous thromboembolism was 38% higher for women ages 35 and older and 64% higher for black women. Other significant risk factors included thrombophilia, lupus, heart disease, sickle cell disease,obesity, fluid and electrolyte imbalance, postpartum infection,and transfusion. The risk factor with the highest odds ratio, 51.8(38.7- 69.2) was thrombophilia. Conclusion: The incidence of pregnancy-related venous thromboembolism was higher than generally quoted. Women ages 35 and older, black women, and women with certain medical conditions and obstetric complications appear to be at increased risk.Objective： The purpose of this study was to estimate the incidence, risk factors, and mortality from pregnan- cy-related venous thromboembolism. Study design： The Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project of the Agency for Heahhcare Re- search and Quality for the years 2000 to 2001 was queried for all pregnancy-related discharges with a diag- nosis of venous thromboembolism. Results： The rate of venous thromboembolism was 1.72 per 1000 deliveries with 1.1 deaths per 100, 000. The risk of venous thromboembolism was 38% higher for women ages 35 and older and 64% higher for black women. Other sig- nificant risk factors included thrombophilia, lupus, heart disease, sickle cell disease, obesity, fluid and electrolyte imbalance, postpartum infection, and transfusion. The risk factor with the highest odds ratio, 51.8（38.7- 69. 2） was thrombophilia. Conclusion： The incidence of pregnancy-related venous thromboembolism was higher than generally quoted. Women ages 35 and older, black women, and women with certain medical conditions and obstetric complications appear to be at increased risk.

关 键 词：静脉血栓栓塞 危险因素 产后感染 发生率 死亡率 妊娠期 血栓形成倾向 妊娠相关 

分 类 号：R543.6[医药卫生—心血管疾病]