葡萄牙布拉加皮肤真菌病的20年调查  

A twenty-year survey of dermatophytoses in Braga, Portugal

作　　者：Valdigem G.L. Pereira T Macedo C. F. Rodrigues 吴佳纹 

机构地区：[1]Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, 4710- 057 Braga, Portugal Dr.

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第9期52-53,共2页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: Modifications in social habits together with the increase of emigration have contributed not only to increased dermatophytoses but also to an altered etiology. During the last few years, Braga has suffered a radical change from a rural to a cosmopolitan life-style. Methods: A statistical study of dermatophytoses and the etiology of their causative agents was performed by a retrospective survey carried out among patients of Hospital de S o Marcos, Braga, Portugal, from 1983- 2002. In this study, a total of 10- 003 patients were analyzed. Results: Over this period the frequency of dermatophytoses, as defined by the recovery of a dermatophyte in culture, was found to be 23.6% , whereas nondermatophytic infections accounted for 7.0% . Analysis of the clinical form s and the isolated fungi supports that the dermatophyte species have a predilection for certain body areas (P ≤ 0.01). Age is a very important factor regarding the occurrence of dermatophytoses (P ≤ 0.0001), with a correlation between increasing age and infection, positive for Trichophyton rubrum and negative for Microsporum canis. Overall the gender of the patients is not an association factor for the development of dermatophytoses; however, significant differences were detected in the distribution of some etiologic agents (P ≤ 0.05). Conclusions: The results showed the main etiologic agent of dermatophytoses to be Trichophyton rubrum (37.4% ). Moreover, dermatophytoses are both decreasing and showing a new profile in Braga, and a pronounced decrease of Trichophyton megninii was observed throughout the study.Background： Modifications in social habits together with the increase of emigration have contributed not only to increased dermatophytoses but also to an altered etiology. During the last few years, Braga has suffered a radical change from a rural to a cosmopolitan life-style. Methods： A statistical study of dermatophytoses and the etiology of their causative agents was performed by a retrospective survey carried out among patients of Hospital de Saeio Marcos, Braga, Portugal, from 1983-2002. In this study, a total of 10 - 003 patients were analyzed. Results： Over this period the frequency of dermatophytoses, as defined by the recovery of a dermatophyte in culture, was found to be 23.6%, whereas nondermatophytic infections accounted for 7.0%. Analysis of the clinical form s and the isolated fungi supports that the dermatophyte species have a predilection for certain body areas （P ≤ 0. 01）. Age is a very important factor regarding the occurrence of dermatophytoses （P ≤ 0. 0001）, with a correlation between increasing age and infection, positive for Trichophyton rubrum and negative for Microsporum canis. Overall the gender of the patients is not an association factor for the development of dermatophytoses; however, significant differences were detected in the distribution of some etiologic agents （P≤ 0. 05）. Conclusions： The results showed the main etiologic agent of dermatophytoses to be Trichophyton rubrum （37.4%） . Moreover, dermatophytoses are both decreasing and showing a new profile in Braga, and a pronounced decrease of Trichophyton megninii was observed throughout the study.

关 键 词：皮肤真菌病 葡萄牙 红色毛癣菌 皮肤癣菌 回顾性调查 犬小孢子菌 显著性差异 发病率 

分 类 号：R756.05[医药卫生—皮肤病学与性病学]