干扰素在哺乳动物早期胚胎发育中的作用  

Research Progress in the Roles of Interferons During Mammalian Early Embryonic Development

作　　者：齐冰[1,2] 何新[1] 常正尧[3] 陈清轩[1] 

机构地区：[1]中国科学院遗传与发育生物学研究所 [2]泰山医学院泰安271016 [3]泰山医学院

出　　处：《中国生物工程杂志》2006年第8期123-126,共4页China Biotechnology

基　　金：国家"973"计划资助项目(2000016107)

摘　　要：干扰素是由多种细胞产生的可溶性糖蛋白,具有广泛的抗病毒、抗肿瘤和免疫调节作用。但是越来越多的实验结果表明干扰素在哺乳动物胚胎植入子宫、怀孕的维持以及早期胚胎发育中发挥着重要作用。结合本实验室的研究工作对干扰素的作用机制和近年来这一领域的研究进展做一综述。Interferons （IFNs）is glycoprotein secreted by many kinds of cells. It has multiple roles in antivirus, anti-tumour and immunity regulation. More and more evidences have proved that IFNs may play important roles not only in implantation and maintenance of pregnancy, but also during early embryo development. The mechanism of IFNs and progress of its role in early embryonic development were summarized.

关 键 词：干扰素 早期胚胎发育 哺乳动物 

分 类 号：Q132.4[生物学—普通生物学]