90例糖尿病患者血液流变学分析  

Hemorheological analysis of 90 diabetic patients.

作　　者：林丽英[1] 谢勇[1] 王莹莹[1] 郑冰冰[1] 

机构地区：[1]海南省农垦总局医院检验科,海南海口570311

出　　处：《中国热带医学》2006年第9期1641-1641,1649,共2页China Tropical Medicine

摘　　要：目的探讨糖尿病患者与健康人血液流变学各项指标变化情况。方法排除年龄、体重及病程等因素影响后,通过压力传感式血液流变学分析仪检测90例糖尿病患者与86例健康人的血液流变学6项指标,分析其异常特点。结果糖尿病病人的全血高切粘度、全血低切粘度、血浆粘度、血纤维蛋白原、全血还原粘度5项指标与正常对照组比较,改变有统计学意义;红细胞压积无明显差异。结论糖尿病患者多伴有血液流变学的改变,改善血液流变状态从而改善微循环是减少并发症的重要措施之一。Objective To observe the changes of hemorheological parameters in patients with diabetes mellitus. Methods The hemorheological parameters from 90 patients with diabetes mellitus and 86 controls were determined by shell cup viseometer. The factors of age, body weight and state of the disease excluded. Results The whole blood viscosity （ both at height shear and low＇ s shear rate）, plasma fibrinogen concentrations and the estimated whole blood viscosity of the diabetes patients were significantly higher than those of the controls. There no significant difference in hematocrit in subject and control groups were observed. Conclusion There are variations of hemorheological parameters in patient with diabetes mellitus. It is one of the important measures to improve hemorheological conditions in patients with diabetes.

关 键 词：糖尿病 血纤维蛋白原 红细胞压积 全血粘度 

分 类 号：R587.1[医药卫生—内分泌]