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作 者:鲁延林[1] 张悦安[1] 徐旭[1] 陈万安[1] 朱志祥[1]
出 处:《临床医药实践》2006年第9期650-652,共3页Proceeding of Clinical Medicine
摘 要:目的:观察二茬头皮在大面积深烧伤手术中的应用效果。方法:对大面积烧伤需要手术切痂头皮移植的思者,常规用电动或气动取皮刀在头部连续切取两层表皮,厚度0.07~0.12mm。将两层表皮制作成小邮票皮,规格为3mm×3mm,间隔3mm移植。外层以异体皮移植。供皮区和移植区创面喷涂表重组人表皮生长因子外用溶液。头皮创面加压包扎,第二天打开敷料,创面半暴露,以红外线灯烤,以表重组人表皮生长因子外用溶液局部喷湿创面,每日1次,约每10cm×10cm面积4000IU,同时皮下注射重组生长激素10U,每日2次,5d为1个疗程。3~10d头皮长好,就行下一次手术。结果:共13例患者97个部位.烧伤面积最小70%,最大94%,平均(83.92±6.65)%,均为大面积深烧伤患者,其中深二度平均(33.46±23.03)%,三度平均(47.16±24.20)%,进行了手术。每次头皮供皮面积3.5%,表层以及二茬皮实际提供7%的皮肤,可覆盖面积30%~40%。术后观察小邮票皮98%~100%成活。3~10d头皮长好,每例患者手术3~8次,愈合时间最短28d,最长54d,平均(36.31±12.99)d。6个月后头部皮肤供区7例毛发生长如伤前,1例稀疏,系取皮过厚所致;早期进行综合抗瘢痕治疗,外观满意。结论:二茬头皮在大面积深烧伤手术中的应用效果满意。Objective:To evaluate the effect of second layer of scalp in the repair of excised severe burn wounds. Methods:The donor sites of two layer of scalp epidermis were grafted,of the thickness about 0.07~0.12 mm,harvested by electric or air dermatome and of the interval about 3 mm, 3 mm×3 mm stamp size free skin grafting,outside which were covered with homograft. The donor and the transplant area were spouted with rhEFG at the level of 4000 IU/10 cm × 10 cm. The head wound were wrapped with pressure and changed dressing the second day,leaving which semi-exposed,roasted by infrared light and spouted with rhEFG qd. The patients were injected with recombinant human growth hormone(10 U ,bid ,i. h. ),of which one treatment period was 5 days. Another operation was done as soon as the scalp recovered in 3~10 days. Results:This method was used in a total of 97 donor sites of 13 patients from May 2002 to November 2005,whose TBSA was from 70 %to 94% and whose mean TBSA was (83.92±6.65)%. Operation were done on these severe burned patients whose mean deep two degree were (33.46±23.03)% and whose mean three degree were(47.16±24.20)%. The first and second layer of scalp could supply 7% skin and could cover 30%~40%surface of the body. 98%~100% stamp size freeskin made from the second layer of the scalp survived and the donor sites healed good enough 3~10 days after the operation. All the burn wound cicatrized in 28~54 days. With the average of (36.31±12.99) days. Of the 13 eases 12 regained normal hair and 1 had sparseness hair 6 month later because of too thick skin cutting and satisfied appearance was obtained with the anti-scar treatment. Conclusions :Second layer of scalp is useful in the repair of excised severe burn wounds.
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