在离子液体中利用Perkin反应合成肉桂酸  

Synthesis of cinnamic acid in ionic liquid

作　　者：杨新宇[1] 陈大茴[1] 王建光[2] 

机构地区：[1]温州医学院药学院 [2]温州医学院基础学院,浙江温州325000

出　　处：《化学研究与应用》2006年第9期1135-1136,共2页Chemical Research and Application

基　　金：温州市科技计划项目(G2003055)资助;浙江省教育厅科研项目20030782资助

摘　　要：Cinnamic acid was synthesized by Perkin reaction in anhydrous potassium carbonate as catalyst,ionic liquid as solvent.The optimal process conditions were obtained as follows:n（PhCHO）:n（Ac2O）:n（K2CO3）=1∶1.2∶1.1,and refluence time was 2h when the refluence temperature was 160℃.The yield of cinnamic acid could reach 80.8%.Cinnamic acid was synthesized by Perkin reaction in anhydrous potassium carbonate as catalyst,ionic liquid as solvent. The optimal process conditions were obtained as follows： n （ PhCHO ） ： n （ Ac2O） ： n （ K2CO3 ） = 1：1.2：1.1, and refluence time was 2h when the refluence temperature was 160℃. The yield of cinnamic acid could reach 80. 8%.

关 键 词：肉桂酸 PERKIN反应 离子液体 碳酸钾 

分 类 号：O622.5[理学—有机化学]