平衡超滤法改善体外循环术后患儿肺功能的研究  

The study of through balance ultrafiltration to improve pulmonary function after exreacorporeal circulation

作　　者：孙跃东[1] 

机构地区：[1]长春市儿童医院,吉林130061

出　　处：《中国优生与遗传杂志》2006年第9期119-120,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的对比研究婴幼儿先天性心脏病体外循环(CPB)中应用平衡超滤法和不应用超滤细胞因子IL-6水平的变化及对术后肺功能影响。方法将20例患儿随机分成对照组和实验组(平衡超滤组),分别于转流前,术后1h及2d取血采用酶联免疫吸附试验(ELISA)法进行白介素6检测,对比两组气道阻力,呼吸机辅助时间和ICU监护时间。结果实验组术后白介素6明显降低于对照组,实验组呼吸机辅助时间,ICU监护时间均短于对照组。结论平衡超滤法滤除细胞因子可改善体外循环术后患儿肺功能。Objective： To contrast the changes of IL -6 and pulmonary function in children with congenital heart disease between the group adopting balance uhrafihration in exreacorporeal circulation and the control group without balance ultrafihration. Methods： 10 cases of serum was obtained from the group adopting balance uhrafihration , and otheer 10 cases from the control group without balance uhrafihration. The level of IL-6 was detected by Enzyme- linked immunoadsordent assay （ELISA） at preoperative, postoperative 1 hour and two days, respectively. At the same time , comparing airway resistance, the time using breathing apparatus and monitoring time in ICU. Results ： After operation , the average level of Iil - 6 in observing group was much lower than that in serum from the control group, and the time using reathing apparatus and caring intensivly was much shorter than those in the control group. Conclusion： Through balance ultrafiltration, pulmonary function may be improved owing to filtering cytokine after exreacorporeal circulation.

关 键 词：平衡超滤 体外循环 肺功能 

分 类 号：R726.5[医药卫生—儿科]