升白方靶向给药治疗放、化疗引起白细胞减少症30例疗效观察  被引量:4

Treatment of Leukopenia Due to Radiotherapy and Chemotherapy by Target Medication of Shengbai Fang: A Clinical Observation of 30 Cases

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作  者:韩桂玲[1] 王微[1] 符思[1] 王颖[1] 

机构地区:[1]卫生部中日友好医院中医脾肺科,北京100029

出  处:《新中医》2006年第10期34-35,共2页New Chinese Medicine

摘  要:目的:观察升白方靶向给药对肿瘤放、化疗引起白细胞减少症的疗效。方法:将57例经放、化疗引起白细胞减少的恶性肿瘤患者随机分为2组。靶向给药组30例,采用超声电导仪经足三里靶向给予升自方(由黄芪、党参、自术、山药、枸杞子、补骨脂等组成)治疗;对照组27例,采用促白细胞生成药(包括升白胺、利血生、鲨肝醇和维生素B4等)治疗。疗程均为7天。观察治疗前后外周血白细胞计数变化以评定临床疗效。结果:靶向给药组显效10例,有效14例,无效6例,总有效率为80%;对照组显效7例,有效10例,无效10例,总有效率为63%。2组疗效比较,差异有显著性意义(P<0.05)。结论:升白方经足三里靶向给药可以明显改善放、化疗引起的白细胞减少症。Objective: To observe the influence of target medication of Shengbai Fang (SBF,升白方) for leukopenia due to radiotherapy and chemotherapy. Methods: 57 tumorous cases with leukopenia due to radiotherapy and chemotherapy were allocated to 2 groups randomly. The target medication group (30 cases) was treated by SBF (composed of Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Fructus Lycii, Fructus Psoraleae, etc. ) by ultrasonic conduc-tometer target medication to Zusanli point; the control group (27 cases) by berbamine, leucogen, scyllitol and vitamin B4, etc. 7 days constituted the course of treatment. The change of peripheral WBC count before and after treatment were applied to evaluate the curative effect. Results: In target medication group, 10 cases were marked effective, 14 cases effective and 6 cases ineffective, the total effective rate was 80% , and 7, 10, 10 and 63% in control group respectively (P<0. 05). Conclusion: Target medication of SBF can marked improve the leukopenia due to radiotherapy and chemotherapy.

关 键 词:白细胞减少症 升白方 中药离子透入  足三里 抗肿瘤联合化疗方案 副作用 

分 类 号:R273.052[医药卫生—中西医结合]

 

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