复方呋喃西林栓剂的配制及质量控制  

Prepration and Quality Control of Compound Furacilin Suppository

作　　者：罗东[1] 冉光炳[1] 刘晶[1] 

机构地区：[1]第三军医大学西南医院药学部,重庆400038

出　　处：《中国药业》2006年第16期34-35,共2页China Pharmaceuticals

摘　　要：目的制备复方呋喃西林栓剂并建立其质量标准。方法以呋喃西林与雌二醇为主药、明胶甘油为基质制备栓剂,采用紫外分光光度法测定栓剂中呋喃西林的含量,测定波长为371.5nm。结果呋喃西林浓度在5.0～9.0μg/mL范围内与吸收度线性关系良好,r=0.9999,平均回收率及RSD分别为100.25%和1.27%。结论制备方法简便,结果满意。Objective To prepare the compound furacilin suppository and to establish the quality standard for the suppository. Methods The main ingredients of the suppository were furacilin and estradiol and the base materials were gelatin and glycerin. To measure the content of furacilin by spectrophotometry,and the wavelength was 371.5 nm. Results It was a good linear relationship in 5.0-9.0 μg/mL for furacilin, and the mean recovery rate was 100. 25%. RSD was 1.27%. Conclusion This method is simple,quick and accurate.

关 键 词：呋喃西林 配制 质量控制 

分 类 号：R944.23[医药卫生—药剂学] R984[医药卫生—药学]