N,N'-二正辛基-3,3'-二硫代二丙酰胺的合成  

Synthesis of N,N'-di-n-octyl-3,3'-dithiodipropionamide

作　　者：王贤丰[1] 杨建平[1] 邬宁昆[1] 刘晓梅 

机构地区：[1]宁波工程学院,浙江宁波315016 [2]宁波龙欣精细化工有限公司,浙江宁波313040

出　　处：《农药》2006年第10期669-671,共3页Agrochemicals

基　　金：宁波市青年(博士)基金资助项目(2005A60024)

摘　　要：研究了异噻唑啉酮的关键中间体N,N'-二正辛基-3,3'-二硫代二丙酰胺的合成。以丙烯酸甲酯为原料,经亲核加成、脱硫精制及酰胺化反应制得目的产物,总收率可达80%。同时详细讨论了反应物配比、反应温度及时间等因素对收率的影响。The key intermediate of N,N＇-di-n-octyi-3,3＇-dithiodipropionamide for preparing isothiazoione was synthesized starting from methyl acrylate by nucleophilic addition, purification with desuifurization and amidating, the total yield reaches 80%. The effects on the yield by reaction agent relative ratio, reaction temperature, reaction time had been also discussed.

关 键 词：异噻唑酮 N N′-二正辛基-3 3′-二硫代二丙酰胺 合成 

分 类 号：TQ450.6[化学工程—农药化工]