植物miRNA的功能及其作用机制  

Advances in Studies on the Function and Mechanism of Plant MicroRNA

作　　者：张松莲[1] 曾富华[1] 喻宁华[1] 饶力群[2] 

机构地区：[1]湛江师范学院应用生命科学研究所,广东湛江524048 [2]湖南农业大学生物科学与技术学院,长沙410128

出　　处：《热带亚热带植物学报》2006年第5期444-450,共7页Journal of Tropical and Subtropical Botany

基　　金：广东省高校自然科学研究项目(Z03062);广东省自然科学基金(5011730)资助

摘　　要：miRNAs是真核生物中的一类5’端带磷酸基团、3’端带羟基、长度在22nt左右的内源性非编码调控RNAs。miRNAs在控制植物的发育、开花时序、新陈代谢、应激反应等方面起着重要的作用。已知植物miRNAs在转录后水平上抑制基因表达,主要是通过导致mRNA的裂解,对抑制目标转录物的翻译起作用。另外其也能在转录水平上通过决定目标染色体位点的甲基化而起作用。对植物miRNAs的功能及作用机制的研究现状做一综述。miRNAs are approximately 22-nucleotide endogenesis noncoding regulated RNAs in eukaryotes that have phosphate group at 5＇end and hydroxy group at 3＇end, which attract extensive attention in recent years. Scientists are now on the threshold of a better understanding how miRNAs works, miRNAs plays an important role in controlling plant development, florescence time, metabolism, response to stress, etc. Plant miRNAs are known to repress gene expression post-transcriptionally, mainly by guiding mRNA cleavage but also by attenuating the translation of target transcripts. In addition, it has been shown that plant miRNAs can also act at the transcriptional level by directing the methylation of target chromosomal loci. This paper reviews recent researches on the function and mechaism of plant microRNA.

关 键 词：综述 MIRNA SIRNA RISC DICER 目标mRNA裂解 翻译抑制 

分 类 号：Q943.2[生物学—植物学]