背向散射技术在多巴酚丁胺负荷试验诊断冠心病中的应用价值  

Values of dobutamineand and integrated backscatter in diagnosis of coronary artery disease

作　　者：王小丛[1] 杨晓英[1] 赵丽荣[1] 姜亚秋[2] 

机构地区：[1]吉林大学第一医院电诊科,吉林长春130021 [2]吉林大学第一医院心内科,吉林长春130021

出　　处：《吉林大学学报（医学版）》2006年第5期926-928,共3页Journal of Jilin University：Medicine Edition

基　　金：吉林省科技厅科研基金资助课题(20030419-06)

摘　　要：目的:探讨背向散射技术(IBS)在多巴酚丁胺负荷超声心动图(DSE)诊断冠心病中的应用价值。方法:31例临床可疑为冠心病患者接受多巴酚丁胺负荷试验(10、20及40μg·kg-1·min-1),以冠脉造影结果为金标准,比较DSE状态下二维超声心动图(2D)与背向散射技术诊断冠心病的敏感性、特异性及符合率。结果:冠状动脉狭窄者在大剂量(40μg·kg-1·min-1)DSE中背向散射积分周期变异幅度(CVIB)低于静息状态,DSE负荷下的CVIB值与静息状态比较差异具有显蓍性(P<0·001)。DSE-2D诊断冠心病的敏感性、特异性和符合率分别为80%、72%和77%,DSE-IBS诊断冠心病的敏感性、特异性和符合率分别为90%、72%和83%。结论:多巴酚丁胺负荷试验与背向散射技术结合,可评价冠心病患者的心肌运动状态,提高诊断冠心病的敏感性,有临床应用价值。Objective To evaluate the values of integrated backscatterr （IBS） and dobutamine stress echocardiography （DSE） in the diagnosis of coronary artery disease （CAD）. Methods Thirty-one suspected CAD patients received DSE and IBS analysis before selective coronary angiography （SCA）. Using SCA results as the golden standard of the diagnosis, the diagnostic sensitivity （Se）, specificity （Sp）, and accuracy rate （Ac） of conventional eye-view and DSE-cyclic variation integrated backscatter （CVIB） were compared. Results The CVIB of myocardial segments perfused by stenotic coronary artery was smaller than that of segments perfused by patent coronary artery during high dose of DSE. For conventional DSE eye-view method, the Se, Sp, and Ac were 80%, 72% and 77%, while that of DSE-CVIB were 90%, 72% and 83%, respectively. Conclusion IBS is a valuable method in assessing the myocardial wall motion in DSE, and the combination of the two methods can improve the diagnostic accuracy rate of CAD.

关 键 词：超声心动描证术 压力 冠状动脉疾病 背向散射积分 

分 类 号：R541.4[医药卫生—心血管疾病] R540.45[医药卫生—内科学]