颈动脉粥样硬化斑块与急性脑梗死患者血脂、血压关系的探讨  

Relationship between atherosclerosis of the carotid artery with plasma lipoprotein blood pressure in patients with ischemic stroke

作　　者：于兰芳[1] 王娘娣[1] 袁波[2] 童晓欣[2] 王双双[3] 王丹军[3] 

机构地区：[1]北京大学深圳医院干部保健科,深圳518036 [2]北京大学深圳医院神经内科,深圳518036 [3]北京大学深圳医院B超室,深圳518036

出　　处：《中国实用神经疾病杂志》2006年第5期9-10,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨急性脑梗死患者血脂浓度、血压与颈动脉粥样硬化斑块的关系。方法应用彩色多普勒超声检查急性脑梗死患者的颈动脉内膜—中膜厚度、斑块数和性状,同时检测血压,查血脂;121例急性脑梗死患者根据有无高血压分为脑梗死组47例、高血压并发脑梗死组74例,年龄相匹配的正常对照组35例。各项数据用SPSS10.0软件统计分析。结果脑梗死合并高血压组颈动脉粥样硬化斑块发生率最高(69.7%),且以软斑及混合斑为主,脑梗死组次之(59.6%),正常组最低(20%)。有颈动脉粥样硬化斑块与无颈动脉粥样硬化斑块相比,血清LDL-C水平明显升高。结论颈动脉粥样硬化斑块是脑梗死的重要危险因素,高血压及高LDL-C血症是颈动脉粥样硬化的危险因素。Objective To study the relationship between atherosclerosis of the carotid artery with plasma lipoprotein and blood pressure in patients with ischemic stroke. Methods Carotid intima -media thickness and carotid vascular plaque was performed with color dop pier ultrasonography on 121 patients which were divided into the following groups：cerebral infarction group （n= 47） and cerebral infarction with hypertension （n=74）. Plasma lipoprotein and blood pressure were tested and contrasted with 35 healthy subjects matching in sex and age. Results The prevalence of carotid atheroscalerosis（CAls） in cerebral infarction group, cerebral infarction with hypertension and control subjects were 69.7 %,59.6 %,20 % repectively. The rate of AS in patients with cerebral infarction and cerebral infarction with hypertension were significantly higher than control group （P〈0. 05）. Plasma LDL-C was significantly higher in carotid atheroscalerosis plaque than control. Conclusion There is internal relation between carotid atheroscalerosis and plasma lipoprotein and blood pressure.

关 键 词：脑梗死 血脂 血压 颈动脉粥样硬化斑块 彩色多普勒超声检查 

分 类 号：R543.4[医药卫生—心血管疾病] R743.33[医药卫生—内科学]