大鼠延髓腹面尾端加压区与头端加压区心血管效应的差异  

ON THE DIFFERENCE OF CARDIOVASCULAR EFFECTS BETWEEN CAUDAL VENTROLATERAL MEDULLA PRESSOR AREA (CVMP) AND ROSTROLATERAL MEDULLA PRESSOR AREA (rVMP)

作　　者：戴秀中[1] 潘燕霞[1] 白玉山[1] 陈 贾秉钧[1] 

机构地区：[1]福建医学院生理教研室

出　　处：《生理学报》1996年第4期405-409,共5页Acta Physiologica Sinica

摘　　要：雄性Ｗｉｓｔａｒ大鼠５６只，乌拉坦麻醉，双侧脑区微量注射谷氨酸钠，观察延髓腹面尾端加压区（ｃＶＭＰ）与头端加压区（ｒＶＭＰ）心血管效应的差异。结果表明：ｃＶＭＰ的升压效应弱于ｒＶＭＰ，不伴随明显的心率效应，ｒＶＭＰ升压效应强于ｃＶＭＰ兼有明显的心率增加。在谷氨酸钠兴奋作用下，ｒＶＭＰ抑制动脉压力感受反射，而ｃＶＭＰ易化该反射。提示两者对心血管功能的影响具有不同的神经途径和机能意义。In 56 urethane anesthetized Wistar rats, bilateral microinjection of glutamate (Lglu) was used to observe the difference of cardiovascular effects between caudal ventrolateral medulla pressor area (cVMP ) and rostral ventrolateral medulla pressor area (rVMP). The results showed that the pressor effect of cVMP was weaker than that of rVMP and was not accampanied by responses in heart rate. In the latter case, an increase of heart rate was involved. The baroreflex was inhibited when rVMP was activated by L-glu but facilitated when cVMP was activated. The above results suggest that the pathway and functions of the cardiovascular effects of rVMP are differnt from those of cVMP.

关 键 词：延髓腹外侧面 心血管效应 

分 类 号：R338.22[医药卫生—人体生理学]