中国六城市中老年人群X射线腰椎骨关节炎流行病学分析  

Epidemiological analysis of radiographic lumbar spine osteoarthritis in middle-aged and elderly population in six cities of China

作　　者：李宁华[1] 张耀南[2] 张毅[1] 王坤正[3] 李恩[4] 朱汉民[5] 金大地[6] 陶天遵[7] 杨静[8] 薛庆云[2] 黄公怡[2] 

机构地区：[1]卫生部北京医院流行病学研究室,北京市100730 [2]卫生部北京医院骨科,北京市100730 [3]西安交通大学第二医院骨科,陕西省西安市710004 [4]河北医科大学中西医结合研究所,河北省石家庄市050017 [5]上海华东医院,上海市200040 [6]南方医科大学南方医院脊柱骨病外科,广东省广州市510515 [7]哈尔滨医科大学第二附属医院骨外二科,黑龙江省哈尔滨市150086 [8]四川大学华西医院骨科,四川省成都市610041

出　　处：《中国临床康复》2006年第40期12-14,共3页Chinese Journal of Clinical Rehabilitation

基　　金：国家"十五"科技攻关计划资助项目(2004BA702B06)~~

摘　　要：目的:了解中国中老年人群X射线腰椎骨关节炎患病率分布。方法:调查时间为2005-06/08。①从中国六大行政区(西北,华北,华东,中南,东北,西南)选出六城市(西安,石家庄,上海,广州,哈尔滨,成都),用分层多阶段整群抽样方法,抽取4824名40岁及以上具有正式户口常住男女人群进行X射线腰椎骨关节炎的流行病学问卷调查(包括一般情况、现病史、既往史、体格检查、X射线片检查情况和疾病诊断6个方面,共计94个问题141个变量指标),并进行X射线片腰椎正侧位投照。②X射线腰椎骨关节炎诊断标准为Kellgren&Lawrence分级二级及以上者。③采用EpiInfo6.0和SPSS10.0软件计算患病率和卡方检验。结果:①六城市X射线腰椎骨关节炎总患病率为46.0%,各城市按年龄标化后患病率的排列顺序为:上海(70.8%)>广州(60.9%)>成都(46.4%)>哈尔滨(46.2%)>西安(34.2%)>石家庄(24.9%),各城市患病率比较差异显著(P<0.01)。②六城市X射线腰椎骨关节炎男性47.6%,女性44.6%,性别患病率差异有显著性意义(P<0.05);X射线腰椎骨关节炎患病率随年龄增长而升高(P<0.01);城乡X射线腰椎骨关节炎患病率差异有非常显著性意义(P<0.01)。结论:国内中老年男女X射线腰椎骨关节炎患病率均较高,应当重视和加强对中老年人群腰椎骨关节炎的预防和控制。AIM：To understand the distribution of prevalence of radiographic lumbar spine osteoarthritis （OA） in Chinese old people. METHODS： The investigation was performed from June to August 2005. （1）A total of 4 824 persons who had formal residence certification and over 40 years old were selected from 6 cities （Xi＇an, Shijiazhuang, Shanghai, Guangzhou, Harbin and Chengdu） of 6 administration regions （northwest, northern China, eastern China, central south, northeast and southwest） of China with stratified-multi-step-cluster sampling method. All subjects received lumbar spine OA epidemiology investigation （containing general condition, present history, past history, physical inspection, X-ray inspection and disease diagnosis, totally 94 problems and 141 variance indexes）, and X-ray was con ducted in lumbar spine in the right and side. （2） Patients with the grade of Kellgren ＆ Lawrence in diagnostic criterion of radiographic lumbar spine OA of grade two or above. （3） Prevalence rate and significance test were calculated with Epilnfo 6.0 and SPSS 10.0 software. RESULTS： （1） The total knee osteoarthritis prevalence rate was 46.0% in the six cities, which was 70.8% in Shanghai, 60.9% in Guangzhou, 46.4% in Chengdu,46.2% in Harbin, 34.2% in Xi＇an, and 24.9% in Shijiazhuang. There was significant difference in the prevalence rate among each city （P 〈 0.01 ）. （2） The prevalence rate of males in six cities was 47.6% and that of females was 44.6%, and there were significant differences in the prevalence of radiographic lumbar spine OA between different sexes （P 〈 0.05）. The prevalence rate of radiographic lumbar spine OA increased with the age increasing （P 〈 0.01）, and there were significant differences between urban and rural areas （P 〈 0.01）. CONCLUSION： The prevalence of radiographic lumbar spine OA is very high in domestic middle-aged and elderly people. The prevention, treatment and control of radiographic lumbar spine OA are very important to o

关 键 词：中老年人 放射摄影术 腰椎关节 骨关节炎 患病率 

分 类 号：R684.3[医药卫生—骨科学]