F-box蛋白质在植物生长发育中的功能  

The Function of F-box Protein in Plant Growth and Development

作　　者：秘彩莉[1] 刘旭[1] 张学勇[2] 

机构地区：[1]中国农业科学院作物科学研究所农业部作物品种资源与生物技术重点实验室 [2]中国农业科学院作物科学研究所

出　　处：《遗传》2006年第10期1337-1342,共6页Hereditas（Beijing)

基　　金：国家自然科学基金(编号:30370881)~~

摘　　要：在真核生物中,泛素介导的蛋白降解途径参与了许多生物学过程。SCF复合体是一种非常重要的E3泛素连接酶,在植物中研究的最为深入。F-box蛋白包含一个F-box基序,是SCF复合体的一个亚基,它决定了底物识别的特异性。目前,从各种植物中已鉴定出大量的F-box蛋白质,它们参与了植物激素(乙烯,生长素,GA,JA)的信号传导以及自交不亲和、花器官发育等生物学过程,F-box蛋白还参与了植物的胁迫反应。最新研究结果显示,一个F-box蛋白TIR1是生长素的受体。因此,F-box蛋白质介导的泛素化蛋白质降解途径可能是植物基因表达调控的重要机制。Ubiquitin-mediated proteolysis is involved in many biological processes in eukaryotes. SCF complex is a very important ubiquitin E3 ligase which has been exploited very well in plants. F-box protein characterized by an F-box motif is a subunit of SCF complex, which works as determinant in substrate recognition. Currently, many F-box proteins have been identified in plants which are involving in hormone （e.g., ethylene, auxin, gibberellin and jasmonate ） signal transduction and biological processes, such as self-incompatibility and floral development. F-box proteins may also participate stress response in plants. Recent study suggested that the Arabidopsis F-box protein TIR1 is an auxin receptor. Therefore, F-box protein mediated proteolysis may be an important gene expression mechanism in plants.

关 键 词：泛素 SCF复合体 F-box蛋白质 蛋白质降解 信号传导 

分 类 号：Q946[生物学—植物学]