某固废拆解基地母乳中多氯联苯含量及其婴儿的暴露风险  

PCBs concentrations in human milk collected from a polluted area——Exposure risk for feeding infants

作　　者：徐承敏[1] 俞苏霞[1] 蒋世熙[1] 吴南翔[1] 张幸[1] 

机构地区：[1]浙江省医学科学院卫生学研究所,杭州310013

出　　处：《卫生研究》2006年第5期604-607,共4页Journal of Hygiene Research

基　　金：浙江省自然科学基金(No.202011);浙江省卫生厅医药卫生科研基金资助项目(No.2000A042)

摘　　要：目的通过测定桌固废拆解基地妇女乳汁中多氯联苯（PCBs）的浓度，了解该地区母体的负荷水平和类二噁英PCBs分布情况，并且对婴儿通过母乳摄入多氯联苯的风险进行评估。方法在拆解区和对照区分别采集20和12份母乳，用气相色谱测定母乳中总PCBs（t-PCBs）的浓度，并对两地区各一份混合母乳样进行类二噁英PCBs检测。结果拆解区和对照区母乳中t-PCBs浓度为0．39～3．92μg／g脂肪和0～0．46μg／g脂肪（只检测出1例）。拆解区和对照区PCBs总TEQ值分别为59pg／g fat和6pg／g fat。结论拆解区妇女乳汁中t-PCBs高于大多数国家和地区的水平，其婴儿每日通过母乳类二噁英摄入量远远大于WHO推荐的成人每日耐受量。Objective To determine the concentration of PCBs and the distribution of dioxin-like compounds in human milk collected from a polluted area where discarded electronic equipment is dismantled, and to evaluate the risk for feeding infants. Methods The authors collected 20 and 12 milk samples from the polluted area and nearby town, respectively. Milk samples were analyzed for total PCBs （t-PCBs） by gas chromatography, and two mixed milk samples from the two areas were detected the distribution of dioxin-like compounds. Results t-PCBs in human milks of polluted area and control area were 0.39 - 3.92μg/g fat and 0.46μg/g（only one sample was detectable）, respectively. The TEQ of PCB126 contribute to total TEQ of dioxin-like compounds was similar to other countries and regions. The TEQs of PCBs of the polluted and control area were 59pg/g fat and 6pg/g fat, respectively. Conclusion The TEQ of PCBs of polluted area was much higher than other countries and regions, and the dioxin-like compounds intake of infants was much higher than the Tolerable Daily Intake （TD1） for dloxin recommended by WHO.

关 键 词：母乳 多氯联苯 类二噁英 婴儿 风险 

分 类 号：R17[医药卫生—妇幼卫生保健]