加替沙星连续静脉滴注与序贯给药治疗泌尿生殖系统感染的成本-效果分析  

Treating Genitourinary Infections with Gatifloxacin by Continuous Intravenous Drip or Sequential Therapy: Cost-effectiveness Analyses

作　　者：胥鹏飞[1] 董传海[1] 程静[1] 邢军[1] 任艳玲[1] 

机构地区：[1]山东莱芜市人民医院,莱芜市271100

出　　处：《中国药房》2006年第19期1480-1481,共2页China Pharmacy

摘　　要：目的评价加替沙星2种不同给药方案治疗泌尿生殖系统感染的成本-效果。方法将76例泌尿生殖系统感染患者随机分为A、B组,各38例,其中A组采用加替沙星注射液连续静脉滴注,B组采用加替沙星注射液/片序贯给药,并对2种方案进行成本-效果分析。结果2组在有效率、细菌清除率及不良反应发生率方面差异无显著性(P>0.05),但A组的治疗成本却明显高于B组(P<0.01),且成本-效果比A组高于B组。结论对泌尿生殖系统感染,采用序贯给药治疗不但安全、有效,而且更加经济、合理。OBJECTIVE：To evaluate the cost -effectiveness of gatifloxacin for genitourinary infections by continuous intravenous drip or sequential therapy.METHODS： A total of 76 patients with genitourinary infections were randomized into 2 groups： 38 cases in group A were assigned to receive gatifloxacin injection by continuous intravenous drip, another 38 cases in group B to receive gatifloxacin injection/ tablet by sequential design.Cost- effectiveness analysis was performed on the 2 groups.RESULTS： No significant difference was noted between 2 groups in effective rates, bacterial clearance rates, and incidences of ADRs（P〉 0.05）, but the treatment cost in group A was significantly higher than in group B（P〈0.01）, and the cost- effec（iveness ratio in group A was also higher than in group B.CONCLUSION： The sequential therapy of gatifloxacin is safe,effective, economical and rational for genitourinary infections.

关 键 词：泌尿生殖系统感染 加替沙星 连续静脉滴注 序贯给药 成本-效果分析 

分 类 号：R956[医药卫生—药学]