核中含有羧基官能团的聚合物胶束的高效制备  

High-yield Preparation of Polymeric Micelles with Carboxyl Groups in the Core

作　　者：王辉[1] 陈道勇[1] 江明[1] 

机构地区：[1]复旦大学高分子科学系

出　　处：《高等学校化学学报》2006年第10期1996-1998,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:20574014和20528405)资助.

摘　　要：Polymeric micelles with carboxyl groups in the core(PMCC)were prepared by chemical cross-linking induced micellization of chlorinated polystyrene-b-poly(acrylic acid)(PS-b-PAA)by glycol in dichloromethane.The crosslinking of chlorinated PAA blocks results in the formation of micelle core,whereas PS block chains form the micelle shell.The chlorination of PAA produces anhydride groups,which make carboxyl groups during the crosslinking reaction with glycols,hence the resultant micelles contain carboxyl groups in the core.As the concentration of polymers can be as high as 50 g/mL,therefore,PMCC can be prepared with a high efficiency,and the powder micelle product was obtained by direct precipitation in methanol-water mixture.The PMCC were characterized by means of FTIR,1H NMR,DLS and SEM.Polymeric micelles with carboxyl groups in the core（PMCC） were prepared by chemical cross-linking induced micellization of chlorinated polystyrene-b-poly （acrylic acid）（ PS-b-PAA ） by glycol in dichloromethane. The crosslinking of chlorinated PAA blocks results in the formation of micelle core, whereas PS block chains form the micelle shell. The chlorination of PAA produces anhydride groups, which make carboxyl groups during the crosslinking reaction with glycols, hence the resultant micelles contain carboxyl groups in the core. As the concentration of polymers can be as high as 50 g/mL, therefore, PMCC can be prepared with a high efficiency, and the powder micelle product was obtained by direct precipitation in methanol-water mixture. The PMCC were characterized by means of FTIR, 1^H NMR, DLS and SEM.

关 键 词：化学交联反应诱导胶束化 核中含有羧基官能团的聚合物胶束 酰氯化 

分 类 号：O631[理学—高分子化学]