肝硬化门静脉高压症患者断流术后转归的影响因素分析  

Influential factors for the consequence of devascularization in patients with liver cirrhosis and portal hypertension

作　　者：梅斌[1] 陈孝平[1] 刘飞龙[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院肝脏外科中心,湖北省武汉市430030

出　　处：《世界华人消化杂志》2006年第24期2452-2455,共4页World Chinese Journal of Digestology

摘　　要：目的:研究肝硬化门静脉高压症患者断流术后转归的影响因素．方法:回顾性分析行断流术的肝硬化门静脉高压症患者158例．根据术后并发症情况将患者分为高危组和一般组2组．将其作为因变量,将23个临床指标作为自变量,进行Logistic回归分析．结果:影单因素分析显示,高危组和一般组凝血酶原时间(PT,P=0．007)、Child分级(P= 0．001)、术中所见肝硬化程度(P=0．002)、B型超声测得盆腔腹水前后径值(P=0．023)、胃镜所见食道胃底静脉曲张程度(P=0．010)有显著性差异．Logistic回归分析显示,Child分级、PT和术中所见肝脏硬化程度在两组间仍有显著差异．结论:肝硬化门静脉高压症患者断流术后转归的影响因素为Child分级、PT和术中所见肝脏硬化程度．AIM： To investigate the influential factors for the consequence of devascularization in patients with liver cirrhosis and portal hypertension. METHODS： The clinical data of 158 patients with liver cirrhosis and portal hypertension, who received devascularization operation, were retrospectively analyzed. The patients were divided into high-risk and common group according to the complications after operation. Regarded as independent variables, 23 clinical factors were analyzed using Logistic regresstion. RESULTS： Single-factor analysis showed that the prothrombin time （PT）, Child grades, the degrees of liver cirrhosis with naked eyes during operation, the values of anteroposterior diameter tested by B ultrasound, and the degrees of esophageal gastric varicose were significantly different between high-risk and common group （P = 0.007; P = 0.001; P = 0.002; P= 0.023; P = 0.010）. Logistic regression analysis showed that the PT, Child grades, the degrees of liver cirrhosis were also significantly different between the two groups. CONCLUSION： The larization in patient risk factors of devascuwith liver cirrhosis and portal hypertension are Child grade, PT and the degrees of liver cirrhosis with naked eyes during operation.

关 键 词：肝硬化 门静脉高压症 断流术 LOGISTIC回归分析 

分 类 号：R657.34[医药卫生—外科学]