纳洛酮与氨茶碱并用治疗早产儿呼吸暂停疗效观察(附50例报告)  

Clinical observation of naloxone plus aminophylline in the treatment of premature apnea

作　　者：夏雪梅[1] 李晓春[1] 孔少云[1] 

机构地区：[1]安徽省安庆市立医院儿科,246003

出　　处：《临床肺科杂志》2006年第6期723-724,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察纳洛酮与氨茶碱联合治疗早产儿呼吸暂停的临床疗效。方法将100例早产儿随机分组，治疗组（50例）与对照组（50例），治疗组与对照组均应用氨茶碱治疗呼吸暂停，始按5mg／kg静滴，继按2．5mg／kg，12h1次维持，治疗组加用纳洛酮，首次按0．1mg／kg以0．03～0．04mg／kg·h输入，观察两组呼吸暂停时间。结果治疗组总有效率明显优于对照组（P〈0．01）。结论纳洛酮与氨茶碱联合治疗早产儿疗效显著。Objective To explore the efficiency of naloxone plus aminophylline on treating premature apnea. Methods 100 patients were randomly divided into groups, treatment group（50） and control （50）, all cases received aminophtylline treatment. Treatment group was added naloxone with an initial does of 0.1 mg/kg, followed by 0. 1 mg/kg with 0. 03 - 0. 04 mg/kg · h pumped. Results The results showed that of control effective rate of the treatment group was obviously higher that of control group （x^2 = 11.78,P 〈 0. 01 ）. Conclusion Naloxone plus aminophylline in treating premature apnea is effective.

关 键 词：早产儿 呼吸暂停 纳洛酮 氨茶碱 

分 类 号：R722.6[医药卫生—儿科]