β-酮酸酯的不对称加氢反应研究进展  

Research Progress on Asymmetric Hydrogenation of β-Keto Ester

作　　者：吴进 

机构地区：[1]宜宾卫生学校,四川宜宾644000

出　　处：《西昌学院学报（自然科学版）》2005年第3期69-72,共4页Journal of Xichang University(Natural Science Edition)

摘　　要：潜手性酮不对称加氢生成的手性仲醇是合成手性药物和精细化学品的重要中间体,近年来,成了人们研究的热点。本文综述了β-酮酸酯在多相、均相和两相体系中不对称加氢的最新进展。The asymmetric hydrogenation of prochiral ketones is an important field in a variety of chemical processes for the synthesis of pharmaceuticals and fine chemical. It has become one of the most attractive field. The research progress of asymmetric hydrogenation of β-keto ester by metal chiral catalyst in recent years are reviewed.

关 键 词：Β-酮酸酯 不对称加氢 对映选择性 

分 类 号：O621.3[理学—有机化学]