An Unexpected Discovery in the Willgerodt-Kindler Reaction of Acetophenone--the Formation of the 4-（Benzoylthiocarbonyl）morpholine  

作　　者：刘玮炜 赵跃强 许瑞波 唐丽娟 胡宏纹 

机构地区：[1]Department of Chemical Engineering, Huaihai Institute of Technology, Lianyungang, Jiangsu 222005, China [2]Department of Chemistry, Nanjing University, Nanjing, Jiangsu 210093, China

出　　处：《Chinese Journal of Chemistry》2006年第10期1472-1475,共4页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （No. 20072016）, the Natural Science Foundation of Jiangsu Education Department （No. 03KJB 150009） and the Subject Foundation of Huaihai Institute of Technology （No. XK01009）.

摘　　要：The Willgerodt-Kindler reaction of acetophenone was studied. Apart from the normal product 4-（benzylthiocarbonyl）morpholine, another product 4-（benzoylthiocarbonyl）morpholine was obtained unexpectedly. The structure of the latter was confirmed by 1R, IH NMR spectra and X-ray diffraction analysis. The mechanism of the reaction was discussed.The Willgerodt-Kindler reaction of acetophenone was studied. Apart from the normal product 4-（benzylthiocarbonyl）morpholine, another product 4-（benzoylthiocarbonyl）morpholine was obtained unexpectedly. The structure of the latter was confirmed by 1R, IH NMR spectra and X-ray diffraction analysis. The mechanism of the reaction was discussed.

关 键 词：4-（benzylthiocarbonyl）morpholine 4-（benzoylthiocarbonyl）morpholine ACETOPHENONE Willgerodt-Kindler reaction crystal structure 

分 类 号：O626.4[理学—有机化学]