青光眼非穿透滤过性手术的基础研究进展  

Recent advances in study on non-penetrating filtering surgery

作　　者：贺春梅[1] 王竫华[1] 王大博[1] 

机构地区：[1]青岛大学医学院附属医院眼科

出　　处：《眼科研究》2006年第5期557-560,共4页Chinese Ophthalmic Research

摘　　要：非穿透滤过性手术是一类新型的抗青光眼手术,主要包括非穿透深层巩膜切除术、外部小梁切除术及黏弹物质小管切开术。与传统小梁切除术相比,非穿透滤过性手术(NPFS)具有术后早期并发症发生率低,术后视力恢复快等优点。目前,NPFS仍处于不断发展完善的过程中。现从手术区的形态学观察、房水动力学、房水引流机制、各种植入材料的生物相容性等方面就基础研究进展进行综述。Non-penetrating filtering surgery is a new surgical way for glaucoma. It includes non-penetrating deep sclerectomy,ab externo trabeculectomy and viscocanalostomy. Through the use of anti-fibrosls drug or implant, Nd：YAG laser goniopuncture,and subconjunctival injections of 5-FU, non-penetrating filtering surgery has the comparable clinical effectiveness to traditional trabeculectomy. But non-penetrating filtering surgery minimizes the risk of postoperative relative hypotony and the complications associated with hypotony,and has quickly recovered visual acuity. Now, non-penetrating filtering surgery still is in a developing stage. The problem of fibrosis and the mechanism of aqueous outflow pathways after non-penetrating filtering surgery still deserve further study. The current progress in morphologic observation of operative site,aqueous dynamics and mechanism of aqueous outflow pathways, and compatibility of implanted materials are summarized.

关 键 词：滤过性手术 青光眼/外科学 巩膜切除术 黏弹物质小管切开术 

分 类 号：R779.6[医药卫生—眼科]