阻塞性睡眠呼吸暂停综合征的实验研究  

Experimental study of obstructive sleep apnea syndrom

作　　者：赵向一[1] 黄席珍[1] 周玉淑[1] 刘雪梅[1] 吴全有[1] 

机构地区：[1]北京协和医院,河南省驻马店地区医院

出　　处：《北京医学》1996年第6期332-334,共3页Beijing Medical Journal

摘　　要：测定了正常人（Ｃ组）、单纯鼾症患者（Ｓ组）及ＰａＣＯ２正常的ＯＳＡＳ患者（Ｏ组）睡前清醒状态下呼吸室内空气时的口腔阻断压（Ｐ０．１）、每分通气量（ＶＥ）等指标，并进行了高氧累进性二氧化碳重复呼吸实验。结果提示，单纯鼾症患者的呼吸中枢驱动水平及呼吸方式与正常人相似；ＯＳＡＳ患者的呼吸方式为浅快呼吸，呼吸中枢驱动性增强，Ｐ０．１及ＶＥ对ＣＯ２反应的敏感性低下。During room air breathing and CO2 rebreathing test, mouth occlusion pressure(P0.1),respiratory rate(RR) and minute ventilation (VE), etc, were measured in three groups. The result showed that, the breathing pattern, respiratory drive and respiratory response to CO2 in simple snoring subjects (group S) were similar to those in normal controls (group C), Patients with OSAS exhibitied a shallow, frequent breathing pattern and increased respiratory drive, compared with the other two groups. The response of P0.1 and VE to CO2 in OSAS patients was markedly lower than in simple snoring and normal subjects.

关 键 词：阻塞性 睡眠呼吸暂停 综合征 重复呼吸 

分 类 号：R563.802[医药卫生—呼吸系统]