冠心病患者血浆脂联素水平变化的探讨  

Stady of the change of plasma adiponectin level in patients with coronary artery disease

作　　者：冯笑梅[1] 冀虎岗[1] 

机构地区：[1]内蒙古自治区医院,呼和浩特010017

出　　处：《江西医学检验》2006年第5期388-389,473,共3页Jiangxi Journal of Medical Laboratory Sciences

摘　　要：目的探讨冠心病患者血浆脂联素(Adiponectin)水平的变化及与动脉粥样硬化发生的关系。方法选择冠心病(CAD)患者40例作为实验组,其中急性冠脉综合征(ACS)20例,包括急性心肌梗死(AMI)11例,不稳定性心绞痛(UA)9例,稳定性心绞痛(SAP)20例;选择排除心血管系统疾病的健康体检者20例作为对照组,分别采血测定血浆脂联素水平,比较冠心病组与对照组血浆脂联素水平有无差异。结果ACS组血浆脂联素水平低于SAP组和对照组,有显著性差异(P<0.05,P<0.001),SAP组与对照组相比差异无统计学意义(P>0.05)。结论脂联素与冠脉病变稳定性显著相关,脂联素水平可做为预测病情,诊断冠心病的一个指标。Objective To investigate the level of plasma adiponeetin in coronary artery dlsease（CAD） and evaluate the correlation between adiponectin and atheroselerosis. Methods 40 patients with CAD were divided into two groups, 20 cases of acute coronary syndrome（ACS）, 20 cases of stable angina peetoris（SAP）. The plasma levels of adiponeetin in groups of ACS and SAP were compared with healthy control group （20 persons）. Results The plasma level of adiponeetin in ACS group was significantly different compared with that of SAP and controls（P 〈 0.05 ,P 〈 0.001）. Conclusion Plasma adiponeetin can reflect the stadility of coronary artery lesion.

关 键 词：脂联素 冠心病 

分 类 号：R446.112[医药卫生—诊断学] R541.4[医药卫生—临床医学]