用图像分析系统定量研究兔早期缺血心肌细胞超微结构的变化  

Quantitative Studies of Ultrastructural Changes in Early Ischemic Myocardial Cells in Rabbits With Image Analysis System

作　　者：温祥云[1] 陈铁军[1] 吕福东[1] 

机构地区：[1]首都医科大学病理学教研室

出　　处：《基础医学与临床》1996年第6期450-453,共4页Basic and Clinical Medicine

摘　　要：应用图像分析仪对结扎冠状动脉造成实验性缺血的兔心肌超微结构进行定量检测。结果显示：线粒体和线粒体外室的体密度随缺血时间延长而加大，线粒体嵴的体密度随缺血时间的延长而减少，缺血４５ｍｉｎ以后即和正常对照有显著性差别。实践证明，图像分析仪在定量超微结构的变化上，具有高度的精确性，故可早期发现病变。ltrastructure quantitative measure of experimental ischemic myocardium of rabbits owing to ligation ofcoronary artery with image analysis instrument.The results showed that the volume density of mitochondriumand mitochondrial intermembrane crack increased according to ischemic time extension;The volume density ofmitochondrial crista decreased according to ischemic time extension;prominent defference occured after 45 min-utes of ischemia,The practice demonstrates that image analysis instrument has marked preciseness in ultrastruc-tural change quantity,so that to detect damages early.

关 键 词：心肌缺血 超微结构 图像分析系统 

分 类 号：R541.402[医药卫生—心血管疾病]