ANCA检测在ANCA相关性小血管炎诊断中的应用  

ANCA Examination's Application in ANCA Relevance Vasculitis Diagnosis

作　　者：陈勇平[1] 詹安南[1] 谢永欣[1] 

机构地区：[1]福建省龙岩市第二医院,福建龙岩364000

出　　处：《海南医学》2006年第11期18-19,共2页Hainan Medical Journal

摘　　要：目的探讨原发性抗中性粒细胞胞浆抗体(ANCA)相关性小血管炎肺部及肾脏的临床表现特点,治疗效果、误诊原因及诊断方法。方法对收治的4例原发性ANCA相关性小血管炎临床资料及误诊原因进行分析,并总结其临床特点及治疗效果。ANCA检测采用IIF和抗原特异ELISA法。结果4例病人都有肺部、肾脏损害,确诊前曾被误诊为肺炎,肺结核,系统性红斑狼疮等。确诊后给予激素联合环磷酰胺治疗,症状短期内迅速好转。结论肺、肾是ANCA相关性小血管炎最常见的累及脏器。误诊原因主要是对本病的特点认识不足。肺、肾损害对治疗的反应较好。及早进行ANCA检测对早期诊断具有重要的临床意义。Objective Discuss the ANCA relevance vasculitis＇ clinical manifestation characteristic in the lungs and the kidney, the treatment effect, reason for misdiagnoses and the diagnosis method. Methods Analyze the clinical document and the reason for misdiagnoses on the four patients with the ANCA relevance vasculitis and sum up the clinical characteristic and the treatment effect. Adopting IIF and ELISE method in ANCA examination. Results All the four patients have suffered from the lungs and the kidney illness, and ever been misdiagnosed for pneumonia, pulmonary tuberculosis and lupus erytyematosus before being diagnosed correctly. After dignosing correctly, giving the hormone and the endoxan treatment to the four patients, they became better rapidly in short time. Conclusions lung and kidney are the organs, which usually are not in normal condition in the ANCA relevance vasculitis. The main reason for misdiagnoses is the poor knowledge on the characteristic of this illness. This kind of treatment is better to lungs and kidney. Early ANCA examination will has the vital clinical significance to the early diagnosis.

关 键 词：ANCA检测 ANCA相关性小血管炎 诊断 

分 类 号：R593.2[医药卫生—内科学]