2型糖尿病性肝损害相关因素分析  

Analysis on factors related to type 2 diabetic hepatic damage

作　　者：王永高[1] 杨萍[1] 

机构地区：[1]广西华锡集团大厂工人医院,南丹547205

出　　处：《广西医学》2006年第10期1503-1504,共2页Guangxi Medical Journal

基　　金：广西医疗卫生科研课题(Z2005169)

摘　　要：目的探讨2型糖尿病患者肝损害的相关因素。方法回顾性总结316例2型糖尿病患者的临床资料,对伴有肝功能损害情况进行分析。结果2型糖尿病性肝损害发生率为13.29%;肝功能异常组患者的血糖、血脂显著高于肝功能正常组(P<0.001);肝功能异常组发生糖尿病肾病、神经病变、视网膜病变、酮症酸中毒等并发症发生率明显升高(P<0.01);经降糖等治疗,肝功能异常组患者的肝功能明显好转(P<0.05)。结论高血糖、高血脂和糖尿病肾病、神经病变、视网膜病变、酮症酸中毒等因素是导致2型糖尿病性肝损害的重要因素,较好地控制血糖是改善2型糖尿病性肝损害患者肝功能的主要措施。Objective To explore the related factors with the type 2 diabetic hepatic damage.Methods The clinical data of 316 patients with type 2 diabetes mellitus were analyzed retrospectively. Results The occurrence rate of hepatic damage in type 2 DM patients was 13.29% ;The levels of blood sugar and blood lipid of hepatic dysfunction group were higher significantly than these in normal group（P〈 0.001 ）;The occurrence rate of hepatic dysfunction in DM combined with diabetic nephropathy or neuropathy or retinopathy or ketoacidosis was rising（P 〈 0.001 ）.The liver function of type 2 diabetic hepatic damage patients can be improved by the hypoglycemic treatment（ P 〈 0.05）. Conclusion Hyperglycemia, Hyperlipemia and diabetic nephropathy, neuropathy, retinopathy, ketoacidosis are considered as major risk factors for diabetic hepatic damage.

关 键 词：2型糖尿病 肝功能异常 血脂 

分 类 号：R587.1[医药卫生—内分泌]