西索米星在大孔弱酸树脂上的吸附研究与传质系数的测定  

STUDY ON ADSORPTION OF SISOMICIN ON MACROPOROUS WEAKLY BASIC ACID RESINS AND DETERMINATION OF MASS TRANSFER COEFFICIENT

作　　者：叶长燊[1] 阮奇[1] 张星[1] 

机构地区：[1]福州大学化学化工学院,福州350002

出　　处：《离子交换与吸附》2006年第5期409-415,共7页Ion Exchange and Adsorption

基　　金：福建省教育厅科研项目(No.JB00093)

摘　　要：对西索米星在大孔弱酸树脂上吸附平衡与动力学进行研究。建立了间歇吸附表面有效扩散模型，利用实验测定了吸附平衡曲线和吸附速率曲线，结合正交配置法、遗传算法直接拟合出固相粒内表面有效扩散系数Dc和液相传质系数kj，其拟合均方根误差不大于0．025．研究结果表明，西索米星在D113树脂上的吸附平衡符合Langmiur方程，吸附速率实验数据与吸附模型数值解拟合良好，表面有效扩散模型能够很好地描述西索米星在弱酸树脂D113上的吸附行为。在实验条件下，表面有效扩散系数Dc约为2.00×10^-8～4．09×10^-8cm^2／s，液相传质系数七，约为9．00×10^-5～2．95×10^-4cm/s．The adsorption equilibrium and kinetics of sisomicin on macroporous weakly basic acid resin were studied. The surface diffusion model was established. The intraparticle surface diffusion coefficient and mass transfer coefficient were obtained by regression of the experiment data of adsorption rate curves compared with orthogonal collocation method and genetic algorithms directly. The mean square errors were not more than 0.025. The results showed that the numerical solutions were agreed with the experiment data of adsorption rate curves. The adsorption equilibrium of sisomicin on macroporous weakly basic acid resin D113 was in accord with Langmuir equation. The adsorption process on Dl13 could be described with the surface diffusion model very well. The intraparticle effective diffusion coefficient was determined to be 2.00x10s-4.09x 10Scm2/s in experimental condition. The internal mass transfer coefficient was 9.00× 106-5cm/s～2.95× 10^4cm/s.

关 键 词：西索米星 弱酸树脂 吸附 表面扩散模型 遗传算法 正交配置法 

分 类 号：O647.3[理学—物理化学]