心脑康胶囊质量标准的研究  

Quality Standard for Xinnaokang Capsule by HPLC

作　　者：刘敏[1] 陈明江 赵海[3] 

机构地区：[1]贵州省食品药品监督管理局稽查局,贵州贵阳550004 [2]贵州省毕节地区药品检验所,551700 [3]贵阳中医学院第二附属医院,贵州贵阳550002

出　　处：《时珍国医国药》2006年第10期2001-2003,共3页Lishizhen Medicine and Materia Medica Research

摘　　要：目的 制定心脑康胶囊的质量控制方法。方法采用薄层色谱法对处方中的丹参、枸杞子、甘草、川芎、牛膝进行定性鉴别，采用高效液相色谱对赤芍的芍药苷进行含量测定。结果 芍药苷在0．1545—1．236μg范围线性关系良好，r=0．9999，平均回收率为99．97％，RSD为2．0％。结论 该方法能准确可靠地进行定性定量检测及有效地控制制剂的质量。Objective To establish the method for quality control of Xinnaokang Capsules. Methods Salvia miltiorrhiza Bge. , Lycium barbarum L. , Gtycyrrhiza uralensis Fisch. , Ligusticum chuanxiong Hort. , Achyranthes bidetata B1. were identified by TLC , and the content of paeoniflorin in Radix Paeoniae Rubra was determined by HPLC. Results Paeoniflorin showed a good linear relationship at a range of 0. 154 5-1. 236μg, r = 0. 999 9. The average recovery was 99.97% , and RSD was 2.0% . Conclusion The method is accurate and reliable , and can control the quality of this preparation effectively.

关 键 词：心脑康胶囊 薄层色谱 高效液相色谱 

分 类 号：R283[医药卫生—中药学] R284.1[医药卫生—中医学]