GC/MS法分析被焚烧人体内脏组织中的氯氮平  

GC/MS analysis of clozopine in burned internal organs tissue of human body

作　　者：陈斌[1] 雷霖 

机构地区：[1]江西省宜春学院医学院生化教研室,336000 [2]江西省宜春市公安局刑警支队刑科所,336000

出　　处：《刑事技术》2006年第5期14-15,共2页Forensic Science and Technology

摘　　要：目的建立GC/MS分析被焚烧人体内脏组织中氯氮平的方法。方法采用试管超声提取、三氯甲烷浸提苯溶解、过柱净化的方法,以岛津QP5050ADB-5MS石英毛细柱分析结果。结果成功检出被焚烧人体内脏组织中氯氮平成分。结论该方法操作简单,准确可靠,适用于中毒及临床药物观察。Objective To establish a GC/MS analysis method for determination of clozapine in burned internal organs tissue of human body. Method The samples were extracted with supersonic wave and trifluoromethane, dissolved with benzene purified then analysed by GC/MS. Results Clozopine in burned internal organs tissue was detected successfully. Conclusion This method is simple, accurate, reliable, and suitable to poison cases, the method also can be used for clinical medicine observation.

关 键 词：被焚烧组织 肝胃 氯氮平 

分 类 号：D919.1[医药卫生—法医学]