复方氧氟沙星涂膜剂的制备与临床疗效观察  

Preparation and observation of clinical effect of compound ofloxacin film

作　　者：孙继平[1] 陶金凤[1] 

机构地区：[1]南京医科大学第三附属医院,江苏仪征211900

出　　处：《药学实践杂志》2006年第5期283-285,共3页Journal of Pharmaceutical Practice

摘　　要：目的：制备复方氧氟沙星涂膜剂并进行疗效观察。方法：采用壳聚糖为基质,制备含氧氟沙星、盐酸丁卡因等药物的涂膜荆,建立制剂质量控制方法,并进行临床疗效观察。结果：该制剂制备工艺简单,质量可靠,治疗复发性口疮有效率达98．8%。结论：该制剂制备工艺简单,疗效确切,临床使用安全可靠。Objective：To prepare compound ofloxacin film and observe its clinical effect. Methods：Chitosan was used as the base material to make compound film which including drugs such as ofloxacin, tetracaine hydrochloride and so on, The quality control method of the film was established and the clinical effect was observed. Results ：The prepare technique is simple and the quality control is reliable. The effective rates of using the film to treat recurrent oral ulcer was 98.8%. Conclusion：Compound ofloxacin film can be prpared easily. The film is reliable curative effect and salty,

关 键 词：氧氟沙星 盐酸丁卡因 壳聚糖 涂膜剂 疗效观察 

分 类 号：R944[医药卫生—药剂学] R988.2[医药卫生—药学]