不稳定性心绞痛患者hs-CRP水平与冠心病危险因素的关系及其与预后的相关性实验观察  

Experimental Observation of Prognostic Relativity of hs-CRP Levels in Patients with Unsteadiness Angina and Coronary Heart Disease Risk Factors

作　　者：袁博[1] 胡章学[2] 王婷[2] 张涛[2] 孟红[2] 

机构地区：[1]陕西省安康市中心医院心内科,陕西安康725000 [2]陕西省安康市中心医院核医学科,陕西安康725000

出　　处：《标记免疫分析与临床》2006年第3期135-136,共2页Labeled Immunoassays and Clinical Medicine

摘　　要：探讨不稳定性心绞痛（UA）患者血浆高敏C-反应蛋白（hs—CRP）水平与冠心病危险因素的关系及其对临床预后预测的价值。对483例入院UA患者进行了血浆hs—CRP检测及其他相关检查，并对其中472例进行1～30（25．6±5．6）个月的随访，以观察其不良心血管事件的发生率。结果发现，472例UA患者中hs—CRP增高者出现高血压、血脂异常、2型糖尿病（2DM）等血管事件的比率显著较高，hs—CRP增高者中吸烟者比例较大。作者认为入院时hs—CRP水平增高是UA患者心血管事件增高的危险预测因子之一。To study relationship of changes of plasma hs-CRP level in patient with unsteadiness angina（UA） and coronary heart disease rick factors in prognosis, plasma hs-CRP levels were measured in 483 patients with UA. The incidence of poor cardiovascular vessels was followed- up for 1 to 30（25.6-＋-5.6） months. Results showed that there was a relatively high proportion of cardiovascular events in subjects suffering from hepertention, lipoprotein abnormity, 2-type diabetes meuitus or smokers of 472 UA patients with increasing hs-CRP. This paper discribed that increasing of plasma hs-CRP levels in the time of admission was a risk prognostic factor for high incidence of cardiovascular events in patients with UA.

关 键 词：冠状动脉疾病 不稳定性心绞痛 C-反应蛋白质 

分 类 号：R541.4[医药卫生—心血管疾病]