循环伏安法测定磺胺嘧啶  

Quantitative Analysis of Sulfadiazine by Cyclic Voltammetry

作　　者：包晓玉[1] 曹书杰[1] 陈欣[1] 陈建国[1] 

机构地区：[1]河南省南阳师范学院化学系,南阳473061

出　　处：《应用化学》2006年第8期858-861,共4页Chinese Journal of Applied Chemistry

基　　金：河南省教育厅自然科学基金资助项目(20021800002)

摘　　要：研究了磺胺嘧啶（SD）在多壁碳纳米管修饰电极上的伏安行为，优化了实验参数（如介质的pH值、修饰剂用量、扫描速度、富集电位和时间等），在此基础上建立了一种直接测定磺胺嘧啶的电化学分析方法。氧化峰电流与磺胺嘧啶的浓度在1．0×10^-6～1．2×10^-4mol／L范围内呈线性关系，检测限为5×10^-7mol／L。用此方法测定了磺胺嘧啶片剂中磺胺嘧啶的含量，结果满意。The electrochemical behavior of sulfadiazine（SD） at multi-wall carbon nanotube（MWNT） modified glassy carbon electrode （GCE） was investigated. The peak current of SD at the MWNT-modified GCE increased significantly in comparison with that at the bare GCE. Based on this, a direct electroanalytical method for determining SD was developed. The experimental parameters such as buffer pH, accumulation potential and time, the amount of MWNT onto the electrode surface and scan rate were optimized. The oxidation peak current increased linearly with the concentration of SD in detection limit was 5.0 × 10^-7 mol/L. With the proposed Keyw cyclic ords sulfadiazine,quantitative analysis,multi-wall voltammetry the range of 1.0 ×10^-6 - 1.2× 10^-4 moL/L. The method, SD in sulfadiazine tablets was determined.

关 键 词：磺胺嘧啶 测定 多壁碳纳米管 修饰玻碳电极 循环伏安法 

分 类 号：O642.5[理学—物理化学]