复发性念珠菌外阴阴道炎发病的相关因素及不同的治疗方法  

The Etiology and different therapy on recurrent vulvovaginal canididiasis

作　　者：陈京芳[1] 

机构地区：[1]南京医科大学附属南京第一医院妇产科,江苏省南京210006

出　　处：《中国基层医药》2006年第9期1409-1411,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨复发性念珠菌外阴阴道炎发病的相关因素并观察微生态制剂对其治疗效果的影响。方法将复发性念珠菌性外阴阴道炎576例通过问卷调查、化验检查得出:滥用抗生素、合并其他病原菌感染、经常阴道冲洗各占发病因素30%、25%和19·1%;同时对其中226例随机分为对照组(单独抗真菌治疗)与治疗组(抗真菌治疗联合微生态制剂)。治疗前、后1周、1个月、2个月进行临床、真菌学疗效分析。结果经抗真菌治疗后,临床、真菌学疗效较好。治疗后2个月,治疗组有效率明显高于对照组(χ2=16·61,P<0·01),复发率低。结论联合微生态制剂治疗复发性念珠菌性外阴阴道炎效果良好。Objective To investigate the causes of and observe the therapeutic effect of microecological preparation on recurrent vulvovaginal candidiasis. Methods 576 patients with recurrent vulvovaginal candidiasis （RVVC） were tested in the papers and the laboratory,and 226 patients were divided into two groups randomly. Control group was treated with anti-fungus drug. The treatment group was treated with microecological preparation combined with anti-fungus drug, The therapeutical effects were observed at the 1st week, 1st month and 2nd month after treatment respectively. Results Factors causing were as follows：use of broad-spectrum antibiotics（30% ）, infection of other pathogens（25 % ）,washing vagina usually（19.1% ）. Anti-fungus drug was effective in the treatment of RVVC. The effective rate of the treatment group was 95.6 %, the control group was 77.0 % at 2nd month after treatment. There was significant difference between the treatment group and the control group（x^2 = 16.61, P （ 0.01 ）. Conclusion Microecological preparation combined with anti-fungus drug is very effective in the treatment of RVVC.

关 键 词：念珠菌病 外阴阴道 微生态制剂 伊曲康唑 咪康唑 

分 类 号：R711.3[医药卫生—妇产科学]