检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
机构地区:[1]中南大学湘雅二医院麻醉科,湖南长沙410011 [2]深圳南山医院麻醉科,广东深圳518000
出 处:《中国医学工程》2006年第4期358-359,363,共3页China Medical Engineering
摘 要:目的观察腰骶部背根神经的脉冲射频对细胞因子TNF-、IL-1和IL-6的影响。探讨脉冲射频可能的机制。方法对18例保守治疗无效的神经根性腰腿痛患者,在影像学引导下进行穿刺定位行背根神经脉冲射频治疗,在行背根神经的脉冲射频前24(hT0),术毕后即时(T1),术毕后6(hT2),术毕后24(hT3),术毕后4(hT4),术毕后72(hT5),分别抽取肘静脉血测定TNF-a、IL-1和IL-6浓度并对患者进行活动时视觉模拟尺度评分(VAS)评分。结果与行背根神经的脉冲射频前24h比较,术毕后6(hT2),术毕后24(hT3),术毕后48(hT4),术毕后72(hT5)的TNF-浓度逐渐下降(P<0.05),与T0比较T3、T4、T5IL-1和IL-6的浓度明显降低。与T0比较T1、T2、T3、T4、T(5,VAS)明显改善(P<0.05)。结论腰骶部背根神经脉冲射频通过降低细胞因子TNF-a、IL-1和IL-6的产生,对神经根性疼痛有治疗作用。[ Objective ] To investigate the effect of pulsed radiofrequency treatment of the lumbosacral dorsal root on cytokines and to explore the potential mechanism of the pulsed radiofrequency. [Methods] Eighteen patients with lumbosacral radicular pain treated with pulsed radiofrequency after conservative therapy were retrospectively evaluated. Blood samples were taken 24 h before pulsed radio-frequency, after operation, 6 h after operation, 24 h after operation, 48 h after operation, and 72 h after operation for determination of plasma levels of TNF-, IL-1, IL-6 activity. The ten-point VAS was used. [Result] The plasma levels of TNF- at T2, T3, T4 and T5 were significantly lower after pulsed radiofrequency, compared to T0- The plasma levels of IL-1, IL-6 at T3, T4 and T5 were significantly lower after pulsed radiofrequency, compared to To. [Conclusion] It suggests that the use of pulsed radiofrequency in the treatment of the lumbosacral radicular pain appears to be effective by inhibiting plasma TNF-a, IL-1, IL-6.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.70