体外循环心内直视手术减少异体输血的探讨  

Effect of reducing homologous blood transfusion in open heart surgery with cardiopulmonary bypass

作　　者：龙建平[1] 熊卫民[1] 盛斌[1] 汪更胜[1] 黄标通[1] 

机构地区：[1]解放军163医院心胸外科,湖南长沙410003

出　　处：《中国医学工程》2006年第4期392-393,395,共3页China Medical Engineering

摘　　要：目的 探讨体外循环心内直视手术少输或不输异体血的方法.方法 对体外循环心内直视手术病人应用术前自体储血,血液回收机回收术中失血以及术前应用促红细胞生成素等综合血液保护方法.结果 实行血液保护措施病人输异体血量为0～2 400mL,平均185 mL/例,对照组输异体血量为300～3 600mL,平均520mL/例,差异有显著性（P＜0.05）.实行血液保护措施病人中41.3%不输异体血,对照组为12%,差异有显著性（P＜0.05）.结论 通过多种血液保护方法可明显减少体外循环心内直视手术的异体输血量.[Objective] To research the methods of reducing homologous blood transfusion in open heart surgery with cardiopulmonary bypass. [Methods] Some blood conservation measures were used in the open heart surgery with cardiopulmonary bypass, such as preoperative autologous blood retention, intraoperative autologous transfusion and preoperative use of erythropoietin （EPO） preoperatively etc. [Results] The volume of homologous blood transfusion of patients with blood conservation measures ranged from 0mL to 2 400 mL, with an average of 185 mL per person. Patients without such blood conservation measures were transfused homologous blood of 300-3600 mL, with an average of 520 mL per person. Significant difference was found between the two groups（P 〈0.05）. Forty-one point three （41.3%） patients with blood conservation measures did not need homologous blood transfusion, and the rate of those without such measures was only 12%（P 〈0.05）. [ Conclusion] Homologous blood transfusion in open heart surgery with cardiopulmonary bypass can be obviously reduced through severalblood conservation methods.

关 键 词：体外循环 血液保护 

分 类 号：R619[医药卫生—外科学]