茜草提取物对大强度耐力训练大鼠心肌线粒体抗氧化能力、ATP酶活性影响的实验研究  

Effect of Rubia cordifolia on myocardial mitochondrial antioxidant ability and activities of ATPase in trained-endurance Rats

作　　者：吕永安[1] 张健[1] 许亚娥[1] 

机构地区：[1]西安建筑科技大学体育系,陕西西安710055

出　　处：《北京体育大学学报》2006年第9期1211-1213,共3页Journal of Beijing Sport University

摘　　要：目的:探讨茜草提取物对大强度耐力训练大鼠心肌线粒体抗氧化能力以及ATP酶活性的影响,为茜草作为运动补剂的开发提供试验依据。方法:通过建立大强度耐力训练大鼠模型,测定心肌线粒体ATP酶、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-Px)活性以及过氧化氢(H2O2)、脂质过氧化产物丙二醛(MDA)的含量,研究茜草提取物对大强度耐力训练大鼠心肌线粒体的保护作用。结果表明,茜草提取物可明显提高大鼠心肌线粒体在大强度耐力运动中的能量供给、抗氧化能力,防止心肌线粒体的氧化损伤,保证了运动中心脏的正常生理功能。The purpose of this study is to discuss the mechanism of Rubia cordifolia impacting to myocar -dial mitochondrial antioxident ability and activities of ATPase in trained-indurance Rats, which can provide examination base for using Rubia cordifolia as sport supplements. Method： Through the changes of activities of myocardial mitochondrial ATPase, SOD, CAT, GSH-Px and the content of myocardial mitochondrial H2O2 and MDA in trained rat are also studied, researching the protecting effects to myocardial mitochondrial . The results show that Rubia cordifolia have a improving effect on the enerey supplying, of myocardial mitochondrial, antioxident ability and preventing, oxidation damnification in intensity sports.

关 键 词：茜草提取物 心肌线粒体 运动能力 

分 类 号：G804.7[文化科学—运动人体科学]