大鼠急性心肌缺血动物实验模型的改进  

Improved Method of Acute Myocardial Ischemic Rat Model

作　　者：罗斌[1] 相磊[2] 江东华[1] 孔小平[1] 张能培[1] 何韵[3] 张斌[4] 阳宇[1] 程灵犀[1] 

机构地区：[1]中山大学基础医学院法医系,广东广州510080 [2]山东大学齐鲁医院病理科,山东济南250012 [3]中山大学肿瘤医院医务科,广东广州510080 [4]泰安市公安局,山东泰安250012

出　　处：《法医学杂志》2006年第5期321-323,共3页Journal of Forensic Medicine

基　　金：国家自然科学基金资助项目(39700167)

摘　　要：目的改进大鼠急性心肌缺血动物实验模型时,提高手术的成功率和动物成活率。方法比较传统方法与改进方法动物试验的成功率。结果传统方法成功率只有60%,改进方法成功率达到90%以上。结论改进后的方法能大大降低手术难度,减少实验费用,优于传统方法。Objective To improve the successful rate of operation and the livability in establishing acute myocardial ischemic rat model. Methods The successful rate of animal experiment is compared between traditional method and improved method. Results The successful rate of improved method was 90%, which was much higher than 30% in successful rate of traditional method. Conclusion The improved method may reduce the difficulty of operation remarkably and cut down the experiment expenditure, which is superior to traditional method.

关 键 词：大鼠 心肌缺血 动物实验模型 

分 类 号：R135.11[医药卫生—劳动卫生]