溶胶-凝胶法制备纳米羟基磷灰石超薄薄膜及其表征  

Sol-gel Preparation of Ultrathin Nano-Hydroxyapatite Coating and Its Characterization

作　　者：杨建华[1] 郭灵虹[2] 李晖[1] 

机构地区：[1]四川大学化学工程学院,成都610065 [2]四川大学分析测试中心,成都610065

出　　处：《生物医学工程学杂志》2006年第5期1075-1079,共5页Journal of Biomedical Engineering

摘　　要：分别使用有机溶胶-凝胶以及无机溶胶作为羟基磷灰石（HA）前驱体，利用浸渍涂层（Dip-coating）技术在钛表面制备纳米超薄薄膜。利用扫描电镜（SEM）和X射线衍射（XRD）表征薄膜形态、微晶尺寸分布（D）和微观应变（ε）。结果表明：在大于400℃热处理后，薄膜开始呈现磷灰石结构；在400℃～600℃范围内，热处理温度对两种磷灰石薄膜D和ε的影响显著；SEM结果证明HA前驱体种类严重影响两种纳米HA薄膜的颗粒团聚尺寸；有机溶胶-凝胶和无机凝胶在钛表面制备的HA薄膜颗粒团聚尺寸分别为25nm和100nm，薄膜厚度分别为2．5μm和5．0μm。浸渍涂层技术制备的HA薄膜表面／界面形态完整，薄膜表面无明显微裂纹。Present study used dip-coating techniques to fabricate uhrathin nano-HA coating on titanium in organic sol-gel of Ca（NO3）2·4H2O and PO（CH3）3 and inorganic sol-gel of Ca（NO3）2·4H2O and （NH4）2HPO4. Scanning electron microscope （SEM） and grazing-incidence X-ray diffraction （XRD） were used to observe the morphology and distribution of crystallite size （D）and lattice strain （ε）of ultrathin nano-HA coating. After heated at 400℃, the apatite structure of coatings on titanium began to appear. At beating temperature of 400℃-600℃, the effect of beating temperature on D and ε of both coatings was obvious. Precursor types significantly affected the particle diameters of nano-HA coatings, which were 25-40 nm for organic sol-gel and about 100 nm for inorganic sol. The thickness of uhrathin nano-HA coatings was 2.5μm for organic sol-gel and 5μm for inorganic sol and morphology of interfaces between coating and titanium was intact and homogenous.

关 键 词：浸渍-薄膜 溶胶-凝胶 羟基磷灰石 X衍射 微晶尺寸分配 微观应变 

分 类 号：R318.08[医药卫生—生物医学工程]