HELLP综合征6例临床分析  

Clinical analysis of six cases with hemolysis,elevated liver enzymes and low platelet count syndrome

作　　者：王玉萍[1] 冯翠萍[1] 陈庆云[1] 吴丽杰[1] 

机构地区：[1]中日友好医院妇产科,北京100029

出　　处：《中日友好医院学报》2006年第5期274-277,共4页Journal of China-Japan Friendship Hospital

摘　　要：目的:分析溶血、肝酶升高及血小板减少综合征(HELLP综合征)的临床特征、诊断、治疗及预后。方法:对我院12年来HELLP综合征6例患者的临床资料进行回顾性分析。结果:完全性HELLP综合征4例,部分性HELLP综合征2例。4例有右上腹痛或不适、茶色尿等特殊表现,2例并没有妊娠期高血压疾病的先兆。主要并发症为弥漫性血管内凝血、脑出血伴脑水肿、急性肾功能衰竭和胎盘早剥等。3例产妇死于严重的并发症,2例死胎原因分别是胎盘早剥、胎儿窘迫。结论:HELLP综合征是一种严重威胁母儿生命的疾病,具有很高的母婴死亡率。应根据其临床特征及早发现和诊断,重症患者应立即中止妊娠并积极防治并发症。Objective：To analyze the clinical character,diagnosis,treatment and prognosis of patients with hemolysis,elevated liver enzymes and low platelet count （HELLP） syndrome.Methods：The clinical data of six cases with HELLP syndrome were analyzed retrospectively during the past twelve years.Results：There were four cases with complete HELLP syndrome and two cases with partial HELLP syndrome.4 cases had special characters such as abdominal pain or discomfort in top right part;tea-color urine etc.Two cases had no sign of hypertension complicating pregnancy.The major complications were disseminated intravascular coagulation, cerebral hemorrhage companied with hydrocephalus,acute renal failure and placental abruption.Three maternal deaths were attributed to severe complications.Two perinatal deaths were related to abrnption placenta and intrauterine asphyxia.Conclusion：HELLP syndrome is a severe life threatening disease,which has high maternal and perinatal mortality.So it should be identified by its special characters and diagnosed as fast as possible.The severe patient should be treated with termination of pregnancy as soon as possible and prevention of severe complications.

关 键 词：妊娠并发症 心血管 HELLP综合征 诊断 预后 

分 类 号：R714.25[医药卫生—妇产科学]