血清MTL、GAS RIA在慢性丙型肝炎患者中的变化及临床意义  

Clinical Significance of Determination of Serum MTL,GAS Levels in Patients with Chronic Hepatitis C

作　　者：马建国[1] 徐素文[1] 李志沭[1] 周漫波[1] 张兆勤[1] 

机构地区：[1]江苏省沭阳县人民医院,223600

出　　处：《放射免疫学杂志》2006年第5期387-388,共2页Journal of Radioimmanology

摘　　要：目的:探讨了血清胃动素(MTL)、胃泌素(GAS)水平在慢性丙型肝炎患者中的变化及意义。方法:应用放射免疫分析对36例慢性丙型肝炎患者进行了血清MTL、GAS水平测定,并与35名正常人作比较。结果:慢性丙型肝炎患者血清MTL、GAS水平非常显著地高于正常人组(P<0.01),且MTL、GAS呈明显的正相关(r=0.8117,P<0.01)。结论:检测慢性丙型肝炎患者血清MTL、GAS水平的变化对疾病的诊断、治疗是一个十分有用的临床检测指标。Objective To explore the changes of serum motilin （MTL） and gastrin （GAS） levels in patients with chronic hepatitis C. Methods Serum MTL, GAS levels were detected with RIA in 36 patients with chronic hepatitis C and 35 controls. Results The levels of serum MTL, GAS were significantly higher in the patients than those in controls （P 〈 0.01）, serum MTL, GAS levels were mutually positive correlated （r = 0.8117, P 〈 0.01）. Conclusion Detection of serum MTL, GAS levels might be of diagnostic and prognostic values in patients with chronic hepatitis C.

关 键 词：慢性丙型肝炎 胃动素 胃泌素 

分 类 号：R512.63[医药卫生—内科学]