抗病毒口服液的质量标准研究  

Study on Quality Standard for Kangbingdu Oral Solution

作　　者：余继英[1] 何林[1] 胡远[1] 孙世明[1] 吴正中[1] 

机构地区：[1]四川省人民医院药剂科,成都市610072

出　　处：《中国药房》2006年第20期1576-1579,共4页China Pharmacy

摘　　要：目的:建立抗病毒口服液的质量标准。方法:采用薄层色谱法对抗病毒口服液中的金银花、鱼腥草、赤芍和射干进行定性鉴别;以高效液相色谱法对其金银花中的绿原酸进行含量测定。结果:抗病毒口服液的金银花、鱼腥草、赤芍、射干薄层色谱中,在与对照药材相应的位置上显相同颜色的斑点;绿原酸检测浓度在3.66～73.20μg/ml范围内与峰面积积分值线性关系良好(r=0.9998),平均回收率为99.7%(RSD=1.52%)。结论:所建质量标准可用于本品的质量控制。OBJECTIVE： To establish the method for quality control of Kangbingdu oral solution.METHODS： TLC was used to identify 4 Chinese medicines, which were Flos Lonicerae, herba houttuyniae, radix paeoniae rubra and rhizoma belamcandae.HPLC was used to determine the content of chlorogenic acid of Flos Lonicerae.RESULTS： In the TLC of flos lonicerae,Herba houttuyniae,Radix paeoniae rubra and rhizoma belamcandae,s position.The linear range of chlorogenic acid was 3.66-73.20/~g/ml（r RSD was 1.52% .CONCLUSION：The method was simple,accurate and quality of this preparation. pots =0. of same color were identified in the corresponding 9 998） .The average recovery was 99.7% and the strong specificity and could be used to control the

关 键 词：抗病毒口服液 薄层色谱法 高效液相色谱法 绿原酸 质量标准 

分 类 号：R927.11[医药卫生—药学]