2-(5-甲基-1,3,4-噁二唑-2-基)-6-二乙氨基荧烷的合成  

Synthesis of 2-(5-methyl-1,3,4-oxadiazole-2-yl)-6-diethylaminofluoran

作　　者：戈乔华[1] 项斌[1] 高建荣[1] 沈卫庆[1] 程水良[1] 

机构地区：[1]浙江工业大学绿色化学合成技术国家重点实验室培育基地,浙江杭州310032

出　　处：《浙江工业大学学报》2006年第5期498-501,共4页Journal of Zhejiang University of Technology

摘　　要：以间氨基苯酚为原料经烷基化和Friedel-Crafts酰基化反应生成了2-羧基-4'-二乙基氨基-2'-羟基二苯甲酮.以对甲氧基苯甲酸为原料经酯化,肼化和环合成反应合成了2-甲基-5-对甲氧基苯基噁二唑.再用2-羧基-4'-二乙基氨基-2'-羟基二苯甲酮和2-甲基-5-对甲氧基苯基噁二唑经环合反应合成了2-(5-甲基-1,3,4-噁二唑-2-基)-6-二乙氨基荧烷.产物经1H NMR,IR,元素分析等检测确定.The 2-Carboxyl-4＇-diethylamino-2＇-hydroxybenzophenone was obtained via alkylation and Friedel-Crafts acylation reaction using 3-diethylaminophenol as the raw material. The 5- Methyl-2-（4-methoxyphenyD-1,3,4-oxadiazole was synthesized by means of esterification, hydraziding and cyclization using p-methoxybenzoic acid. The 2-（5-Methyl-1,3,4- oxadiazole-2-yl）-6-diethylaminofluoran was prepared from 2-carboxyl -4＇-diethylamino -2＇-hydroxybenzophenone and 5-methyl-2-（4-methoxyphenyl）-1, 3,4-oxadiazole. These compounds were identified by IR, 1H NMR, UV and element analysis.

关 键 词：荧烷 嗯二唑 染料 二苯甲酮 功能色素 

分 类 号：TQ225.241[化学工程—有机化工]