提高SOD在外科中老年手术的临床疗效  

Clinical Effect of increasing SOD on Middle-Old Aged Operation Patients

作　　者：宋方闻[1] 黄时杰 钟惟德[3] 

机构地区：[1]广州医学院南大学院,广州510320 [2]广州市红会医院,广州510220 [3]广州医学院附属市一人民医院,广州510180

出　　处：《现代食品与药品杂志》2006年第5期17-19,共3页JOurnal of Modern Food and Pharmaceuticals

摘　　要：目的通过观察患者血液黏稠度、血气(PaO2、SaO2)、一氧化氮合成酶(NOS)的变化,研究提高超氧化物歧化酶(SOD)药物对中老年患者进行手术治疗的影响。方法选择190例中老年需手术患者,实验组100例,服用提高SOD药物益心康泰胶囊,对照组90例不服用该药,用双盲法观察治疗前后各指标的变化。结果实验组的血液黏稠度、PaO2、SaO2、NOS的改善度均较对照组差异有显著性意义(P<0.05)。结论在手术前后应用提高SOD的药物对外科中老年手术病例有降低血液黏稠度、改善血气、降低血栓形成危险的疗效。Objective To observe the effects of increasing SOD drugs on middle-old aged operation patients by observing the change of blood viscosity, PaO2 , SaO2 and NOS. Methods 190 cases were randomly divided into treatment group and control group. Treatment group（n = 100） was treated with Yixinkangtai capsule to increase SOD and control group （n =90） was not treated with this medicine. The change of blood viscosity, PaO2, SaO2 and NOS with double blind therapy were observed. Results Treatment group patients＇blood viscosity, PaO2, SaO2 and NOS were improved significantly in treatment group than that of control group （ P 〈 0.05）. Conclusion Increased SOD medicine has a good clinical effects on reducing blood viscosity, and impoving PaO2, SaO2, NOS, and inhibiting the thrombosis of clot on the middle-old aged operation patients.

关 键 词：提高SOD 中老年患者手术 血液黏稠度 血气(PaO2 SaO2) NOS 

分 类 号：R969.4[医药卫生—药理学]