血清泌乳素在月经周期中的变化规律及其与微量元素的关系  

Periodic variation and relationship of Prolactin serum with trace element in menstrual cycle

作　　者：徐仙[1] 何秉洁[1] 王燕[1] 张莉[1] 毛文军[1] 陈晓燕[1] 

机构地区：[1]宁夏医学院附属医院妇产科 [2]内蒙古乌海市海勃湾矿务局二医院 [3]西安医科大学生殖内分泌研究室

出　　处：《宁夏医学杂志》1996年第5期269-271,共3页Ningxia Medical Journal

摘　　要：本研究应用多项排卵监测指标对３３例月经周期正常的育龄妇女，于卵泡中期、排卵日和黄体中期测定血清泌乳素（ＰＲＬ）及微量元素的含量，以探讨月经周期中ＰＲＬ的变化规律及其与微量元素的相互关系。结果表明：血清ＰＲＬ水平在黄体中期最高，明显高于卵泡中期（Ｐ＜０．０５），在周期中呈递升趋势；卵泡中期血清ＰＲＬ与镍含量呈正相关（ｒ＝０．５６６８，Ｐ＜０．００５），与铜负相关（ｒ＝－０．５３８２，Ｐ＜０．０１）；排卵日ＰＲＬ与铁呈显著正相关（ｒ＝０．６５２６，Ｐ＜０．００１）；黄体中期ＰＲＬ与镍呈负相关（ｒ＝－０．４３６４，Ｐ＜０．０５），且与孕酮浓度呈正相关（Ｐ＜０．０１）。研究提示：血清ＰＲＬ水平存在周期性变化，可能与微量元素之间的相互作用和调节有关。To investigate the regulan variation of prolactin (PRL) in menstrual cycle and its relation with trace element(TE),serum PRL and TE were measured in the mid-follicular,ovulating day mid-luteal phases of 33 normal women The results showed that there were the highest levels of serum PRL in mid-luteal phases( P <0.05);A positive correlation existed between both the PRL and nickel(Ni)(n=0.5668, P <0.05) in mid-folliculan phase and the serum PRL and iron(r=0.6526, P <0.001) in ovulating day;A negative correlation existed between both the serum PRL and coppen(r=-0.5328, P <0.01) in mid-follicular phase and the serum PRL and Ni(r=-0.4364, P <0.05) in mid-luteal phase.It is indicated that the periodic variation of serum PRL in merstrual cycle may have certain interrelationship with TE,PRL in luteal phase can promote corpus luteal function and progesterone syntheses.

关 键 词：月经周期 泌乳素 微量元素 

分 类 号：R711.51[医药卫生—妇产科学]